Expression vector of mouse Rab27A mutant (Q78L) lacking C-terminal geranylgeranylation sites (C219A, C221A).
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External Database mouse Rab27a mouse Mreg Reference sequence |
Sequence (partial) | RDB15185pka01.seq provided by the depositor |
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Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
Terms and conditions set forth by the DEPOSITOR | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature designated by the DEPOSITOR is requested. (J. Cell Sci. 125; 125 (Pt6): 1508-1518, 2012); (Pigment Cell Melanoma Res. 23 (3): 365-374, 2010); (Genes Cells 11 (9): 1023-1037, 2006); (J. Biol. Chem. 289 (16): 11059-11067, 2014) |
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Ordering | Please visit Information of Request for Distribution.[link] Order form [Credit Card Payment ![]() ![]() Material Transfer Agreement (MTA for use for not-for-profit academic purpose) [Word ![]() |
Remarks | This RESOURCE contains a fluorescent protein provided by Prof. Roger Tsien. UCSD's MTA is also required. Please visit Additional Forms section. This RESOURCE is not provided to for-profit organization or for for-profit research by non-profit organizations. |
提供条件 | 利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する(J. Cell Sci. 125; 125 (Pt6): 1508-1518, 2012); (Pigment Cell Melanoma Res. 23 (3): 365-374, 2010); (Genes Cells 11 (9): 1023-1037, 2006); (J. Biol. Chem. 289 (16): 11059-11067, 2014)。 |
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提供依頼 | 手続きの詳細は、「提供申込みについて[link]」をご覧ください。 提供依頼書 [Word ![]() 提供同意書 (MTA、非営利機関による非営利学術研究用)[Word ![]() |
備考 | Prof. Roger Tsienから供与された蛍光タンパク質を含みます。UCSDとのMTA締結が必要です。「申込みに必要な書式」をご覧ください。本件リソースは営利機関および非営利機関による営利目的研究には提供いたしません。 |
Catalog # | Resource name | Availability | Shipping form | Fee (non-profit org.) |
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RDB15185 | pCMV-Mreg delta C/MST-mStr-Rab27A-QL/CA | Under QC test. Please contact us. | DNA solution |
Original reference
Further references such as user reports and related articles (go to bottom)
Featured content
Featured content | Rab family protein (English text) |
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Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.
Original, user report and related articles
original | Ishida, M., The GTPase-deficient Rab27A(Q78L) mutant inhibits melanosome transport in melanocytes through trapping of Rab27A effector protein Slac2-a/melanophilin in their cytosol: development of a novel melanosome-targeting tag. J. Biol. Chem. 289 (16): 11059-11067 (2014). PMID 24584932. |
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reference | Ohbayashi, N., Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes. J. Cell Sci. 125 (Pt 6): 1508-1518 (2012). PMID 22275436. |
reference | Ohbayashi, N., Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. Pigment. Cell Melanoma Res. 23 (3): 365-374 (2010). PMID 20370853. |
reference | Itoh, T., Screening for target Rabs of TBC (Tre-2/Bub2/Cdc16) domain-containing proteins based on their Rab-binding activity. Genes Cells 11 (9): 1023-1037 (2006). PMID 16923123. |
2022.07.27
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