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pEF6-Myc-mouse Optineurin(H486R)

Expression vector of mouse Optineurin (OPTN), H486R mutant, tagged with Myc.

Catalog number RDB16721
Resource name pEF6-Myc-mouse Optineurin(H486R)
Clone info. Expression vector of mouse Optineurin (OPTN) mutant, H486R which is unable to recruit the deubiquitinase cylindromatosis tumor suppressor protein (CYLD), tagged with Myc.
Vector backbone pEF6/myc-His (plasmid)
Selectable markers Amp^r
Gene/insert name mouse Optn cDNA
Depositor|Developer Maruyama, Takashi |
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mouse Optn
          Reference sequence
            
           

          Distribution information

          Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
          Terms and conditions for distribution In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature designated by the DEPOSITOR (J. Biol. Chem. 292(42), 17250-17257, 2017) and an acknowledgment to the DEPOSITOR are requested.
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          提供条件 利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する(J. Biol. Chem. 292(42), 17250-17257, 2017)。利用者は、研究成果の公表にあたって寄託者への謝辞の表明を必要とする。
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          RDB16721 pEF6-Myc-mouse Optineurin(H486R) Under QC test. Please contact us. DNA solution

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          How to cite this biological resource

          Materials & Methods section:

          The pEF6-Myc-mouse Optineurin(H486R) was provided by the RIKEN BRC through the National BioResource Project of the MEXT, Japan (cat. RDB16721).

          Reference section:

          Tanishima, M., Takashima, S., Honda, A., Yasuda, D., Tanikawa, T., Ishii, S., MaruYama, T., Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling. J. Biol. Chem. 292 (42): 17250-17257 (2017). PMID 28882891. [link to RRC of NBRP]

          Further references such as user reports and related articles (go to bottom)

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          QC test results

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          References

          Original, user report and related articles

          original Tanishima, M., Identification of optineurin as an interleukin-1 receptor-associated kinase 1-binding protein and its role in regulation of MyD88-dependent signaling. J. Biol. Chem. 292 (42): 17250-17257 (2017). PMID 28882891. [link to RRC of NBRP]

          2023.08.17

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