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GNP Clone

Catalog number RDB07566
Resource name GNP Clone
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            Featured content Genome Network Project human cDNA clone (English text)
            Featured content Genome Network Project human cDNA clone (Japanese text)


            Original, user report and related articles

            original Kimura, K., Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Genome Res. 16 (1): 55-65 (2006). PMID 16344560.
            original Itoh, M., Constructing ORFeome resources with removable termination codons. Biotechniques 41 (1): 44-48 (2006). PMID 16869512.
            original Otsuki, T., Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries. DNA Res. 12 (2): 117-126 (2005). PMID 16303743.
            original Ota, T., Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. 36 (1): 40-45 (2004). PMID 14702039.
            user report Kamo, M., Discovery of anti-cell migration activity of an anti-HIV heterocyclic compound by identification of its binding protein hnRNP M. Bioorg. Chem. 107: 104627 (2021). PMID 33476868.
            user report Inukai, R., The Novel ALG-2 Target Protein CDIP1 Promotes Cell Death by Interacting with ESCRT-I and VAPA/B. Int. J. Mol. Sci. 22 (3): 1175 (2021). PMID 33503978.
            user report Maruyama, K., Carrier frequencies of antithrombin, protein C, and protein S deficiency variants estimated using a public database and expression experiments. Res. Pract. Thromb. Haemost. 5 (1): 179-186 (2021). PMID 33537542.
            user report Niinae, T., Identification of Endogenous Kinase Substrates by Proximity Labeling Combined with Kinase Perturbation and Phosphorylation Motifs. Mol. Cell. Proteomics. 20: 100119 (2021). PMID 34186244.
            user report Asano, T., Development of a Novel Epitope Mapping System: RIEDL Insertion for Epitope Mapping Method. Monoclon. Antib. Immunodiagn. Immunother. 40 (4): 162-167 (2021). PMID 34424761.
            user report Inoue, H., The interaction of ATP11C-b with ezrin contributes to its polarized localization. J. Cell Sci. 134 (20): jcs258523 (2021). PMID 34528675.
            user report Takamatsu, K., Aging-associated stem/progenitor cell dysfunction in the salivary glands of mice. Exp. Cell Res. 409 (1): 112889 (2021). PMID 34678306.
            user report Nakagawa, T., JMJD2A sensitizes gastric cancer to chemotherapy by cooperating with CCDC8. Gastric Cancer 23 (3): 426-436 (2020) PMID 31677131.
            user report Hatta, D., Activity-dependent cleavage of dyskinesia-related proline-rich transmembrane protein 2 (PRRT2) by calpain in mouse primary cortical neurons. FASEB J. 34 (1): 180-191 (2020). PMID 31914621.
            user report Fujikawa, K., S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein. Biochem. Biophys. Res. Commun. 524 (4): 910-915 (2020). PMID 32051088.
            user report Zhao, Y.F., Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons. Development 147 (6): dev183509 (2020). PMID 32098764.
            user report Miyao, N., TBX5 R264K Acts as a Modifier to Develop Dilated Cardiomyopathy in Mice Independently of T-box Pathway. PLoS One 15 (4): e0227393 (2020). PMID 32236096.
            user report Nakatake, Y., Generation and Profiling of 2,135 Human ESC Lines for the Systematic Analyses of Cell States Perturbed by Inducing Single Transcription Factors. Cell Rep. 31 (7): 107655 (2020). PMID 32433964.
            user report Osada, Y., The Fibrinogen C-terminal Domain Is Seldom C-mannosylated but Its C-mannosylation Is Important for the Secretion of Microfibril-Associated Glycoprotein 4. Biochim. Biophys. Acta. Gen. Subj. 1864 (9): 129637 (2020). PMID 32442478.
            user report Furusawa, Y., Establishment of an Anti-CD20 Monoclonal Antibody (C 20 Mab-60) for Immunohistochemical Analyses. Monoclon. Antib. Immunodiagn. Immunother. 39(4): 112-116 (2020). PMID 32667234.
            user report Asano, T., RIEDL tag: A novel pentapeptide tagging system for transmembrane protein purification. Biochem. Biophys. Rep. 23:100780 (2020). PMID 32715101.
            user report Furusawa, Y., Establishment of C20Mab‑11, a novel anti‑CD20 monoclonal antibody, for the detection of B cells. Oncol. Lett. 20: 1961-1967 (2020). PMID 32724441.
            user report Toma-Fukai, S., Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure. J. Biol. Chem. 295(43): 14630-14639 (2020). PMID 32820047.
            user report Kinoshita-Kikuta, E., Protein-N-myristoylation-dependent phosphorylation of serine 13 of tyrosine kinase Lyn by casein kinase 1γ at the Golgi during intracellular protein traffic. Sci. Rep. 10 (1): 16273 (2020). PMID 33004926.
            user report Yokosawa, T., Tryptophan Depletion Modulates Tryptophanyl-tRNA Synthetase-Mediated High-Affinity Tryptophan Uptake into Human Cells. Genes (Basel) 11 (12): 1423 (2020). PMID 33261077.
            user report Tsurumi, Y., Interactions of the dynein-2 intermediate chain WDR34 with the light chains are required for ciliary retrograde protein trafficking. Mol. Biol. Cell 16: mbcE18100678 (2019). PMID 30649997.
            user report Kawara, H., DCAF7 is required for maintaining the cellular levels of ERCC1-XPF and nucleotide excision repair. Biochem. Biophys. Res. Commun. 519 (1): 204-210 (2019). PMID 31493872.
            user report Ishii, T., In Vitro Modeling of the Bipolar Disorder and Schizophrenia Using Patient-Derived Induced Pluripotent Stem Cells with Copy Number Variations of PCDH15 and RELN. eNeuro 6 (5). pii: ENEURO.0403-18.2019 (2019). PMID 31540999.
            user report Sato, R., Novel biallelic mutations in the PNPT1 gene encoding a mitochondrial-RNA-import protein PNPase cause delayed myelination. Clin. Genet. 93 (2): 242-247 (2018). PMID 28594066.
            user report Hamada, Y., Interaction of WDR60 intermediate chain with TCTEX1D2 light chain of the dynein-2 complex is crucial for ciliary protein trafficking. Mol. Biol. Cell 29 (13): 1628-1639 (2018). PMID 29742051.
            user report Yamada, S., Detection of high CD44 expression in oral cancers using the novel monoclonal antibody, C44Mab-5. Biochem. Biophys. Rep. 14: 64-68 (2018). PMID 29872736.
            user report Kikuchi, K., Map7/7D1 and Dvl form a feedback loop that facilitates microtubule remodeling and Wnt5a signaling. EMBO Rep. 19 (7). pii: e45471 (2018). PMID 29880710.
            user report Funabashi, T., Interaction of heterotrimeric kinesin-II with IFT-B-connecting tetramer is crucial for ciliogenesis. J. Cell Biol. 217 (8): 2867-2876 (2018). PMID 29903877.
            user report Mizuno, H., MicroRNA-101 inhibits the expression of Rhes, a striatal-enriched small G-protein, at the post-transcriptional level in vitro. BMC Res. Notes 11 (1): 528 (2018) PMID 30064488.
            user report Kubota, R., Chemogenetic Approach Using Ni(II) Complex-Agonist Conjugates Allows Selective Activation of Class A G-Protein-Coupled Receptors. ACS Cent. Sci. 4 (9): 1211-1221 (2018). PMID 30276255.
            user report Fujimoto, T., Identification of the physiological substrates of PDIp, a pancreas-specific protein-disulfide isomerase family member. J. Biol. Chem. 293 (48): 18421-18433 (2018). PMID 30315102.
            user report Hirano, T., Intraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors. Mol. Biol. Cell 28 (3): 429-439 (2017). PMID 27932497.
            user report Kondo, H., Mutation in VPS33A affects metabolism of glycosaminoglycans: a new type of mucopolysaccharidosis with severe systemic symptoms. Hum. Mol. Genet. 26 (1): 173-183 (2017). PMID 28013294.
            user report Funabashi, T., Ciliary entry of KIF17 is dependent on its binding to the IFT-B complex via IFT46-IFT56 as well as on its nuclear localization signal. Mol. Biol. Cell 28 (5): 624-633 (2017). PMID 28077622.
            user report Kinoshita, E., Specific glutamic acid residues in targeted proteins induce exaggerated retardations in Phos-tag SDS-PAGE migration. Electrophoresis 38 (8): 1139-1146 (2017). PMID 28112428.
            user report Horigome, T., Sulfated glycosaminoglycans and non-classically secreted proteins, basic FGF and epimorphin, coordinately regulate TGF-beta-induced cell behaviors of human scar dermal fibroblasts. J. Dermatol. Sci. 86 (2): 132-141 (2017). PMID 28209294.
            user report Kawaguchi, K., Tandem UIMs confer Lys48 ubiquitin chain substrate preference to deubiquitinase USP25. Sci. Rep. 7: 45037 (2017). PMID 28327663.
            user report Tomizawa, M., CCAAT/enhancer-binding protein alpha decreases the viability of gastric cancer cells. Oncol. Lett. 13 (6): 4322-4326 (2017). PMID 28599433.
            user report Yoshizawa, R., Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral. Biophys. Physicobiol. 14: 75-84 (2017). PMID 28744424.
            user report Hirano, K., FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1. FEBS Open Bio. 7 (12): 1932-1942 (2017). PMID 29226080.
            user report Ida, L., Receptor tyrosine kinase-like orphan receptor 1, a target of NKX2-1/TTF-1 lineage-survival oncogene, inhibits apoptosis signal-regulating kinase 1-mediated pro-apoptotic signaling in lung adenocarcinoma. Cancer Sci. 107 (2): 155-161 (2016). PMID 26661061.
            user report Tomizawa, M., Transcription Factors and Medium Suitable for Initiating the Differentiation of Human Induced Pluripotent Stem Cells to the Hepatocyte Lineage. J. Cell. Biochem. 117 (9): 2001-2009 (2016). PMID 26773721.
            user report Teng, Y.N., beta-carotene reverses multidrug resistant cancer cells by selectively modulating human P-glycoprotein function. Phytomedicine 23 (3): 316-323, 2016. PMID 26969385.
            user report Katoh, Y., Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex. J. Biol. Chem. 291 (21): 10962-10975 (2016). PMID 26980730.
            user report Hirano, K., LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling The Expression of a Novel Target Gene, HEYL. Stem Cells 34 (7): 1872-1882 (2016). PMID 27018646.
            user report Imamura, Y., Generation of Large Numbers of Antigen-Expressing Human Dendritic Cells Using CD14-ML Technology. PLoS One. 2016 Apr 6;11(4):e0152384 (2016). PMID 27050553.
            user report Kurosawa, N., Novel method for the high-throughput production of phosphorylation site-specific monoclonal antibodies. Sci. Rep. 6: 25174 (2016). PMID 27125496.
            user report Ohta, S., Proteomics analysis with a nano Random Forest approach reveals novel functional interactions regulated by SMC complexes on mitotic chromosomes. Mol. Cell. Proteomics. pii: mcp.M116.057885 (2016).user report PMID 27231315.
            user report Kataoka, K., Mitochondrial cereblon functions as a Lon-type protease. Sci. Rep. 6: 29986 (2016). PMID 27417535.
            user report Kitagaki, J., A Putative Association of a Single Nucleotide Polymorphism in GPR126 with Aggressive Periodontitis in a Japanese Population. PLoS One 11 (8): e0160765 (2016). PMID 27509131.
            user report Suga, A., Identification of Novel Mutations in the LRR-Cap Domain of C21orf2 in Japanese Patients With Retinitis Pigmentosa and Cone-Rod Dystrophy. Invest. Ophthalmol. Vis. Sci. 57 (10): 4255-4263 (2016). PMID 27548899.
            user report Foglizzo, M., Structure and Function of the RING Domains of RNF20 and RNF40, Dimeric E3 Ligases that Monoubiquitylate Histone H2B. J. Mol. Biol. 428 (20): 4073-4086 (2016). PMID 27569044.
            user report Yamaguchi, A., FUS interacts with nuclear matrix-associated protein SAFB1 as well as Matrin3 to regulate splicing and ligand-mediated transcription. Sci. Rep. 6: 35195 (2016). PMID 27731383.
            user report Hashimoto, K., B Cell-Based Seamless Engineering of Antibody Fc Domains. PLoS One 11 (12): e0167232 (2016). PMID 27907066.
            user report Yamamoto, S., Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytes. Sci. Rep. 5: 8505 (2015). PMID 25687367.
            user report Hashizume, O., Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects. Sci. Rep. 5: 10434 (2015). PMID 26000717.
            user report Shintomi, K., Reconstitution of mitotic chromatids with a minimum set of purified factors. Nat. Cell Biol. 17 (8): 1014-1023 (2015). PMID 26075356.
            user report Fujikawa, Y., A practical fluorogenic substrate for high-throughput screening of glutathione S-transferase inhibitors. Chem. Commun. (Camb). 51 (57): 11459-11462 (2015). PMID 26090533.
            user report Sawamura, N., Cereblon is recruited to aggresome and shows cytoprotective effect against ubiquitin-proteasome system dysfunction. Biochem Biophys Res Commun. 2015 Jul 15. pii: S0006-291X(15)30298-9 PMID 26188093.
            user report Shrestha, R., Molecular mechanism by which acyclic retinoid induces nuclear localization of transglutaminase 2 in human hepatocellular carcinoma cells. Cell Death Dis. 6: e2002 (2015). PMID 26633708.
            user report Kogure, H., Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ. Nucleic Acids Res., 42 (5):3152-3163 (2014). PMID 24322300.
            user report Shirafuji, T., The role of Pak-interacting exchange facto-beta phosphorylation at serines 340 and 583 by PKC gamma in dopamine release. J. Neurosci., 34 (28): 9268-9280 (2014). PMID 25009260.
            user report Takanashi, K., Aggregation of ALS-linked FUS mutant sequesters RNA binding proteins and impairs RNA granules formation. Biochem. Biophys. Res. Commun. 452 (3): 600-607 (2014). PMID 25173930.
            user report Takamatsu, K., Degradation of amyloid beta by human induced pluripotent stem cell-derived macrophages expressing Neprilysin-2. Stem Cell Res. 13 (3PA): 442-453 (2014). PMID 25460605.
            user report Oppikofer, M., Dimerization of Sir3 via its C-terminal winged helix domain is essential for yeast heterochromatin formation. EMBO J. 32 (3): 437-449 (2013). PMID 23299941.
            user report Haruta, M., Generation of a large number of functional dendritic cells from human monocytes expanded by forced expression of cMYC plus BMI1. Hum. Immunol., 74 (10): 1400-1408 (2013). PMID 23811433.
            user report Schlam, D., Diacylglycerol kinases terminate diacylglycerol signalling during the respiratory burst leading to heterogeneous phagosomal NADPH oxidase activation. J. Biol. Chem., 288 (32): 23090-23104 (2013). PMID 23814057.
            user report Akizawa, Y., Enhanced expression of myogenic differentiation factors and skeletal muscle proteins in human amnion-derived cells via the forced expression of MYOD1. Brain Dev., 35 (4): 349-355 (2012). PMID 22727434.
            user report Shin, J.W., Establishment of single-cell screening system for the rapid identification of transcriptional modulators involved in direct cell . Nucleic Acids Res., 40 (21): e165 (2012). PMID 22879381.