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Please review the QC test results indicated by check icon below as well as clone information before placing your order.

pCAG-HIVgp

Expression vector of HIV-1 gag and pol for lentivirus vector packaging.

Catalog number RDB04394
Resource name pCAG-HIVgp
Clone info. Expression vector of HIV-1 gag and pol for lentivirus vector packaging.
Comment Commonly requested with pCMV-VSV-G-RSV-Rev (RDB04393).
Vector backbone Plasmid
Selectable markers Kan^r
Gene/insert name HIV-1 gag-pol
Depositor|Developer Miyoshi, Hiroyuki |
Other clones in our bank

External Database
HIV-1 gag-pol

          Reference sequence
            
           
          Sequence RDB04394z.seq
          Remarks, protocol and/or map (pdf) RDB04394.pdf
          Lentiviral plasmid list. [link]

          Distribution information

          Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
          Terms and conditions set forth by the DEPOSITOR The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit academic purpose. The RECIPIENT agrees to expressly describe the late Dr. Hiroyuki Miyoshi as the Developer.
          Ordering Please visit Ordering instruction.[link] 
          Order form 
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          Material Transfer Agreement (MTA, for use for not-for-profit academic purpose)[Word]
          Remarks Remember that you will be working with samples containing infectious virus.
          提供案内 (日本国内) [open/close]

          提供条件 本件研究材料は、非営利機関の非営利学術研究に限って提供する。本件研究材料を利用した研究結果等を発表する際は、本件研究材料が故三好浩之博士により開発されたことを明示する。
          提供依頼 手続きの詳細は、「レンチウイルスベクターの提供申し込み」をご覧ください。
          提供依頼書 [Word]
          提供同意書 (非営利機関による非営利学術研究用)[Word]
          遺伝子組換え生物の受入れ確認書が必要です。当室にご請求ください。
          備考 このリソースはウイルス粒子産生用のため、取扱いに注意が必要です。

          Catalog # Resource name Shipping form Fee (non-profit org.)
          RDB04394 pCAG-HIVgp DNA solution

          Ordering instruction of plasmids [in Japanese] [in English]
          Please review the QC test results indicated by check icon below as well as clone information before placing your order.

          References and tips

          Original reference

          original Miyoshi, H., Development of a self-inactivating lentivirus vector. J. Virol., 72 (10): 8150-8157 (1998). PMID 9733856.

          Further references such as user reports and related articles (go to bottom)

          Featured content

          Featured content Lentivirus Vector (English text)
          Featured content Lentivirus Vector (Japanese text)

          QC test results

          RIKEN BRC has sequenced portions of this material for quality test.
          Please review the QC test results indicated by check icon as well as clone information before placing your order.

          Test sheet RDB04394_040922p1-1.pdf check

          Nucleotide sequence of a portion of this resource (if available).

          Primer: CAG_R1
          Region: CAG pro,HIV-1 gp 5'(HIV-1 gag 5')
          Sequence file: RDB04394_040922a.seq check
          >04394_04394_040922_CAG_R1_A03_03_ABI24.ab1
              1 NNNNNNNNNN NNNNNNNNNN NNNNNNNNNG NGGCGCGNNN NNNNNCGGNG CGGCGCCGGC
             61 AGGAAGGAAA TGGGCGGGGN NGGCCTTCGT GCGTCGCCGC GCCGCCGTCC CCTTCTCCCT
            121 CTCCAGCCTC GGGGCTGTCC GCGGGGGGAC GGCTGCCTTC GGGGGGGACG GGGCAGGGCG
            181 GGGTTCGGCT TCTGGCGTGT GACCGGCGGC TCTAGAGCCT CTGCTAACCA TGTTCATGCC
            241 TTCTTCTTTT TCCTACAGCT CCTGGGCAAC GTGCTGGTTA TTGTGCTGTC TCATCATTTT
            301 GGCAAAGAAT TGATTTGATA CGTACGGTTT CGAGCTCAAG CTTCGAATTC GAGATCTGCC
            361 GCCGCCATGG GTGCGAGAGC GTCAGTATTA AGCGGGGGAG AATTAGATCG ATGGGAAAAA
            421 ATTCGGTTAA GGCCAGGGGG AAAGAAAAAA TATAAATTAA AACATATAGT ATGGGCAAGC
            481 AGGGAGCTAG AACGATTCGC AGTTAATCCT GGCCTGTTAG AAACATCANA AGGCTGTAGA
            541 CAAATACTGG GACAGCTACA ACCATCCCTT CAGACAGGAT CAGAAGAACT TAGATCATTA
            601 TATAATACAG TAGCAACCCT CTATTGTGTG CATCAAAGGA TAGAGATAAA AGACACCAAG
            661 GAAGCTTTAN ACAAGATAGA GGAAGAGCAA AACAAAAGTA AGAAAAAAGC ACAGCAAGCN
            721 NCANCTGACA CAGGACACAN CAATCNNGTC ANCCNAAAAT TACCCTATAG TGNANANCAT
            781 CCANGGGGCA AATGGTACNT CANGCCNTAT CACCTNNAAC TTTTAAATGC NTGGGNNAAN
            841 GTAGNNNNAN ANAANGCTTT CNNNNCCNNA NNTGATANNN CANGTTTTTN AGCNNNNNNT
            901 CNNAANNGNN NNCCNCCCCC ACNNNANTTN NNANCANCNN NNGNCTAAAN NNNNNNGNNG
          961 GGGNNNNANN NNNGNNAGCC NNNNNNNNNN
          //
          Primer: pAxEF_R2
          Region: SV40p(A),RRE,HIV-1 gp 3'(HIV-1 pol 3')
          Sequence file: RDB04394_040922b.seq check
          >04394_04394_A9KqF_pAxEF_R2_A01_01_ABI08.ab1
              1 NNNNNNNANN NNNNNNNNNN NTGTGNNANT TGTGNNGCTA TTGCTTTATT TGTAACCATT
             61 ATAAGCTGCA ATAAACAAGT TAACAACAAC AATTGCATTC ATTTTATGTT TCAGGTTCAG
            121 GGGGAGGTGT GGGAGGTTTT TTAAAGCAAG TAAAACCTCT ACAAATGTGG TATGGCTGAT
            181 TATGATCAGT TATCTAGATC CGGTGGATCC CGGGCCCGCG GAAGCTTGTG TAATTGTTAA
            241 TTTCTCTGTC CCACTCCATC CAGGTCGTGT GATTCCAAAT CTGTTCCAGA GATTTATTAC
            301 TCCAACTAGC ATTCCAAGGC ACAGCAGTGG TGCAAATGAG TTTTCCAGAG CAACCCCAAA
            361 TCCCCAGGAG CTGTTGATCC TTTAGGTATC TTTCCACAGC CAGGATTCTT GCCTGGAGCT
            421 GCTTGATGCC CCAGACTGTG AGTTGCAACA GATGCTGTTG CGCCTCAATA GCCCTCAGCA
            481 AATTGTTCTG CTGCTGCACT ATACCAGACA ATAATTGTCT GGCCTGTACC GTCAGCGTCA
            541 TTGACGCTGC GCCCATAGTG CTTCCTGCTG CTCCCAAGAA CCCAAGGAAC AAAGCTCCTG
            601 CGGCCGCTCC GGAATTCCAT GTGTTAATCC TCATCCTGTC TACTTGCCAC ACAATCATCA
            661 CCTGCCATCT GTTTTCCATA ATCCCTGATG ATCTTTGCTT TTCTTCTTGG CACTACTTTT
            721 ATGTCACTAT TATCTTGTAT TACTACTGCC CCTTCACCTT TCCAGANGAN CTTTGCTGGT
            781 CCTTTCCNAA CTGGATCTCT GCTGTCCCTG TAATAAACNC GAAANNTTTG AATTTTTGTA
            841 ATTTGTTTTT GNAATTCTTT TAGTTTGNAT GNCTGTTGCT ATTATGTCNA CTATTCNTTT
            901 CCCCNGCNNT GNACCCCCCC NANTCCCCCC NNTTTTNTTT TAANNNTGNN GNANNNANNN
          961 NNNGNCNNTT TNNNACNGNN NNNNNNNN
          //
          Primer: HIVgp_F1
          Region: HIV-1 gp 3'(HIV-1 pol 3',D64)
          Sequence file: RDB04394_040922c.seq check
          >04394_04394_A9KqF_HIVgp-F1_C09_09_ABI24.ab1
              1 NNNNNNNNNN NNNNNCNNNN TATGCATTGG GAANCATTCN AGCACAACCA GATAAGAGTG
             61 AATCAGAGTT AGTCAGTCAA ATAATAGAGC AGTTAATAAA AAAGGAAAAA GTCTACCTGG
            121 CATGGGTACC AGCACACAAA GGAATTGGAG GAAATGAACA AGTAGATAAA TTGGTCAGTG
            181 CTGGAATCAG GAAAGTACTA TTTTTAGATG GAATAGATAA GGCCCAAGAA GAACATGAGA
            241 AATATCACAG TAATTGGAGA GCAATGGCTA GTGATTTTAA CCTACCACCT GTAGTAGCAA
            301 AAGAAATAGT AGCCAGCTGT GATAAATGTC AGCTAAAAGG GGAAGCCATG CATGGACAAG
            361 TAGACTGTAG CCCAGGAATA TGGCAGCTAG ATTGTACACA TTTAGAAGGA AAAGTTATCT
            421 TGGTAGCAGT TCATGTAGCC NGTGGATATA TAGAAGCAGA AGTAATTCCA GCAGANACNG
            481 GGCAAGAAAC AGCATACTTC CTCTTAAANT TANCAGGAAN ANGGNNAGTA AAAACAGTNC
            541 NTACNGANNA TGGCNNCNNT TTCNNCNGTA CTNNNGTTNA NGNCNNNNGN NGGNGGNNNG
          601 GGNANNNANN NNNNANTTNN NNTNNNNNNN NNN
          //
          Primer: HIVpol_R
          Region: HIV-1 gp mid(HIV-1 pol 5',HIV-1 gag 3')
          Sequence file: RDB04394_040922d.seq check
          >04394_04394_A9KqF_HIVpol_R_B01_02_ABI08.ab1
              1 NNNNNNNNNN NNNNNNNNNN NNNNCTGNNN NTACTGTCTT ACTTTGATAA AACCTCCAAT
             61 TCCCCCTATC ATTTTTGGTT TCCATCTTCC TGGCAAATTC ATTTCTTCTA ATACTGTATC
            121 ATCTGCTCCT GTATCTAATA GAGCTTCCTT TAATTGCCCC CCTATCTTTA TTGTGACGAG
            181 GGGTCGCTGC CAAAGAGTGA TCTGAGGGAA GCTAAAGGAT ACAGTTCCTT GTCTATCGGC
            241 TCCTGCTTCT GAGAGGGAGT TGTTGTCTCT TCCCCAAACC TGAAGCTCTC TTCTGGTGGG
            301 GCTGTTGGCT CTGGTCTGCT CTGAAGAAAA TTCCCTGGCC TTCCCTTGTG GGAAGGCCAG
            361 ATCTTCCCTA AAAAATTAGC CTGTCTCTCA GTACAATCTT TCATTTGGTG TCCTTCCTTT
            421 CCACATTTCC AACAGCCCTT TTTCCTAGGG GCCCTGCAAT TTTTGGCTAT GTGCCCTTCT
            481 TTGCCACAAT TGAAACACTT AACAGTCTTT CTTTGGTTCC TAAAATTGCC TTTCTGTATC
            541 ATTATGGTAG CTGGATTTGT TACTTGGCTC ATTGCTTCAG CCAAAACTCT TGCTTTATGG
            601 CCGGGTCCCC CCACTCCCTG ACATGCTGTC ATCATTTCTT CTAGTGTCGC TCCTGGTCCC
            661 AATGCTTTTA AAATAGTCTT ACAATCTGGG TTCGCATTTT GGANCAACAA GGTTTCTGTC
            721 ATCCAATTTT TTACCTCTTG TGAAGCTTGC TCGGCTCTTA NAGTTTTATA GAATCGGTCT
            781 ACATAGTCTC TAAAGGGTTC CTTTGGTCCT TGTCTTATGT CCAGAATGCT GGTANGGCTA
            841 TACATTCTTA CTATTTTATT TAATCCCANG NNTATCNNTC TTTNATAGAT TTCTCCNACT
            901 GGGANANGNG GANTATGTGN CATNCNTCCN ATTTGNTNCT GNANNGNNNC NANNANNTNN
          961 CNGNNNTGNN ACNNNCCNNT NNGNNNNNNN NNN
          //
          Primer: SV40pro_ori_F
          Region: SV40 pro_ori,NeoR_KanR 5'
          Sequence file: RDB04394_040922e.seq check
          >04394_04394_040922_SV40pro_ori_F_E03_15_ABI24.ab1
              1 NNNNNNNNNN NNNNNNNNNN CCNCNNCCTC TGNNCTATTC NNGAAGTAGT GAGGANGCTT
             61 TTTTGGAGGC CTAGGCTTTT GCAAAGATCG ATCAAGAGAC AGGATGAGGA TCGTTTCGCA
            121 TGATTGAACA AGATGGATTG CACGCAGGTT CTCCGGCCGC TTGGGTGGAG AGGCTATTCG
            181 GCTATGACTG GGCACAACAG ACAATCGGCT GCTCTGATGC CGCCGTGTTC CGGCTGTCAG
            241 CGCAGGGGCG CCCGGTTCTT TTTGTCAAGA CCGACCTGTC CGGTGCCCTG AATGAACTGC
            301 AAGACGAGGC AGCGCGGCTA TCGTGGCTGG CCACGACGGG CGTTCCTTGC GCAGCTGTGC
            361 TCGACGTTGT CACTGAAGCG GGAAGGGACT GGCTGCTATT GGGCGAAGTG CCGGGGCAGG
            421 ATCTCCTGTC ATCTCACCTT GCTCCTGCCG AGAAAGTATC CATCATGGCT GATGCAATGC
            481 GGCGGCTGCA TACGCTTGAT CCGGCTACCT GCCCATTCGA CCACCAAGCG AAACATCGCA
            541 TCGAGCGAGC ACGTACTCGG ATGGAAGCCG GTCTTGTCGA TCAGGATGAT CTGGACGAAG
            601 AGCATCAGGG GCTCGCGCCA GCCGAACTGT TCGCCAGGCT CAAGGCGAGC ATGCCCGACG
            661 GCGAGGATCT CGTCGTGANC CATGGCGATG CCTGCTTGCC GAATATCATG GTGGAAAATG
            721 GCCGCTTTTC TGGATTCATC GACTGTGGCC GGCTGGGTGT GGCGGACCGC TATCAGGACA
            781 TANCGTTGGC TACCCGNGAT ATTGCTGAAG ANCTTGNCGG CGAATGGGCT GNNCGCTTCC
            841 TCGNGCTTTA CGGNATCGCC GCNCCCGATN CNCAGCGCAT CNCNTTCNAT CGCNNTCTTG
          901 NNNANTNCTN NNNNNCGGGN NTCNGGGGNN NCNAAANGN
          //
          Primer: RRE-M_R
          Region: RRE,HIV-1 gp(HIV-1pol 3'_cPPT_CTS)
          Sequence file: RDB04394_040922f.seq check
          >04394_04394_A9KqF_RRE-M_R_G09_21_ABI24.ab1
              1 NNNNNNNNNA NNNNNGCTGT TGCGCCTCNA TAGCCCTCNG CAAATTGTTC TGCTGCTGCA
             61 CTATACCAGA CAATAATTGT CTGGCCTGTA CCGTCAGCGT CATTGACGCT GCGCCCATAG
            121 TGCTTCCTGC TGCTCCCAAG AACCCAAGGA ACAAAGCTCC TGCGGCCGCT CCGGAATTCC
            181 ATGTGTTAAT CCTCATCCTG TCTACTTGCC ACACAATCAT CACCTGCCAT CTGTTTTCCA
            241 TAATCCCTGA TGATCTTTGC TTTTCTTCTT GGCACTACTT TTATGTCACT ATTATCTTGT
            301 ATTACTACTG CCCCTTCACC TTTCCAGAGG AGCTTTGCTG GTCCTTTCCA AACTGGATCT
            361 CTGCTGTCCC TGTAATAAAC CCGAAAATTT TGAATTTTTG TAATTTGTTT TTGTAATTCT
            421 TTAGTTTGTA TGTCTGTTGC TATTATGTCT ACTATTCTTT CCCCTGCACT GTACCCCCCA
            481 ATCCCCCCTT TTCTTTTAAA ATTGTGGATG AATACTGCCA TTTGTACTGC TGTCTTAAGA
            541 TGTTCAGCCT GATCTCTTAC CTGTCCTATA ATTTTCTTTA ATTCTTTATT CATAGATTCT
            601 ATTACTCCTT GACTTTGGGG ATTGTAGGGA ATGCCAAATT CCTGCTTGAT CCCCGCCCAC
            661 CAACAGGCGG CCTTAACTGT AGTACTGGTG AAATTGCTGC CATTGTCTGT ATGTACTGTT
            721 TTTACTGNCC ATCTTCCTGC TAATTTTAAG AGGAAGTATG CTGTTTCTTG CCCTGTCTCT
            781 GCTGGAATTA CTTCTGCTTC TATATATCCA CTGGCTACAT GAACTGCTAC CAAGATAACT
            841 TTTCCTTCTA AATGTGTACA ATCTAGCTGC CATATTCCTG GGCTACAGTC TACTTGTCCN
            901 TGCATGGCTT CCCNTTTTAN CTGANNTTTA TCACAGCTGG CTACTATTTC TTTTGCTACT
            961 ACAGGNGGNA NGTTNAAANC ACNANNNNTN GNTNNNNNNN TNNNTGNNNN ATTNNNNNNN
          1021 NNN
          //

          Please visit Sequencing and PCR primers for primer information.


          References

          Original, user report and related articles

          original Miyoshi, H., Development of a self-inactivating lentivirus vector. J. Virol., 72 (10): 8150-8157 (1998). PMID 9733856.
          reference Suga, H., Self-formation of functional adenohypophysis in three-dimensional culture. Nature 480 (7375): 57-62 (2011). PMID 22080957.
          reference Ikemoto, M., Autologous transplantation of SM/C-2.6(+) satellite cells transduced with micro-dystrophin CS1 cDNA by lentiviral vector into mdx mice. Mo.l Ther. 15 (12): 2178-2185 (2007). PMID 17726457.
          user_report Hada, M., Highly rigid H3.1/H3.2-H3K9me3 domains set a barrier for cell fate reprogramming in trophoblast stem cells. Genes Dev. 36 (1-2): 84-102 (2022). PMID 34992147.
          user_report , Concurrent Activation of Kras and Canonical Wnt Signaling Induces Premalignant Lesions That Progress to Extrahepatic Biliary Cancer in Mice. Cancer Res. 82 (9): 1803-1817 (2022) PMID 35247892.
          user_report Oikawa, T., Lentiviral expression of calpain-1 C2-like domain peptide prevents glutamate-induced cell death in mouse hippocampal neuronal HT22 cells. In Vitro Cell Dev Biol Anim. 2022 Apr;58(4):289-294 (2022). PMID 35469046.
          user_report Nishida, J., An in vivo orthotopic serial passaging model for a metastatic renal cancer study. STAR Protoc. 2022 Apr 18;3(2):101306 (2022). PMID 35496785.
          user_report Miyamoto, T., Rapid manipulation of mitochondrial morphology in a living cell with iCMM. Cell Reports Methods 1: 100052 (2021).
          user_report Munirah, I., Immortalization of cells derived from domestic dogs through expressing mutant cyclin-dependent kinase 4, cyclin D1, and telomerase reverse transcriptase. Cytotechnology (2021).
          user_report Ikeuchi, M., The tumor suppressor LATS2 reduces v-Src-induced membrane blebs in a kinase activity-independent manner. FASEB J. 35 (1): e21242 (2021). PMID 33368671.
          user_report Miyazaki, S., Establishment of a long-term stable beta-cell line and its application to analyze the effect of Gcg expression on insulin secretion. Sci. Rep. 11 (1): 477 (2021). PMID 33436850.
          user_report Ikeda, A., Colorectal Cancer-Derived CAT1-Positive Extracellular Vesicles Alter Nitric Oxide Metabolism in Endothelial Cells and Promote Angiogenesis. Mol. Cancer Res. 19 (5): 834-846 (2021). PMID 33579815.
          user_report Kato, H., DPYD, down-regulated by the potentially chemopreventive agent luteolin, interacts with STAT3 in pancreatic cancer. Carcinogenesis
          . 2021 Feb 26;bgab017. doi: 10.1093/carcin/bgab017. Online ahead of print. PMID 33640964.
          user_report Maruoka, M., Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane. Mol. Cell 81 (7): 1397-1410.e9 (2021). PMID 33725486.
          user_report Kwon, A.T., Development of p53 knockout U87MG cell line for unbiased drug delivery testing system using CRISPR-Cas9 and transcriptomic analysis. J. Biotechnol. 332: 72-82 (2021). PMID 33836165.
          user_report Kohrogi, K., LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPalpha. Blood Adv. 5 (9): 2305-2318 (2021). PMID 33929501.
          user_report Kawata, K., Odontoblast differentiation is regulated by an interplay between primary cilia and the canonical Wnt pathway. Bone 150: 116001 (2021). PMID 33975031.
          user_report Miyakuni, K., Genome-wide analysis of DNA methylation identifies the apoptosis-related gene UQCRH as a tumor suppressor in renal cancer. Mol Oncol. 2021 Jun 16. doi: 10.1002/1878-0261.13040. Epub ahead of print. PMID 34133843.
          user_report Kodama, S., Progression of melanoma is suppressed by targeting all transforming growth factor‑β isoforms with an Fc chimeric receptor. Oncol. Rep. 46 (3): 197 (2021). PMID 34296292.
          user_report Yamagishi, M., Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. Nat. Commun. 12 (1): 4821 (2021). PMID 34376672.
          user_report Hirano, K.I., LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice. Elife 10: e68227 (2021). PMID 34382935.
          user_report Daimon, E., Macrothrombocytopenia of Takenouchi-Kosaki syndrome is ameliorated by CDC42 specific- and lipidation inhibitors in MEG-01 cells. Sci. Rep. 11 (1): 17990 (2021). PMID 34504210.
          user_report Nanba, D., EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis. J. Cell Biol. 220 (11): e202012073 (2021). PMID 34550317.
          user_report Masaki, T., Calcineurin regulates the stability and activity of estrogen receptor alpha. Proc. Natl. Acad. Sci. U.S.A. 118 (44): e2114258118 (2021). PMID 34711683.
          user_report Sima, F., Mimicking Intravasation–Extravasation with a 3D Glass Nanofluidic Model for the Chemotaxis‐Free Migration of Cancer Cells in Confined Spaces. Adv. mater. Technol. 5: 2000484 (2020).
          user_report Fujii, S., The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation. Lab. Invest. 100 (2): 311-323 (2020). PMID 31857698.
          user_report Ryoden, Y., Functional Expression of the P2X7 ATP Receptor Requires Eros. J. Immunol. 204 (3): 559-568 (2020). PMID 31862710.
          user_report Watanabe, R., SPOP is essential for DNA-protein cross-link repair in prostate cancer cells: SPOP-dependent removal of topoisomerase 2A from the topoisomerase 2A-DNA cleavage complex. Mol. Biol. Cell 31 (6): 478-490 (2020). PMID 31967940.
          user_report Nakamura, T., Tissue-nonspecific alkaline phosphatase promotes the osteogenic differentiation of osteoprogenitor cells. Biochem. Biophys. Res. Commun. 524 (3): 702-709 (2020). PMID 32035618.
          user_report Tanaka, A., Reversible expansion of pancreatic islet progenitors derived from human induced pluripotent stem cells. Genes Cells 25 (5): 302-311 (2020). PMID 32065490.
          user_report Onodera, K., Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs. Mol. Brain 13 (1): 18 (2020). PMID 32070397.
          user_report Orimoto, A., Primary and immortalized cell lines derived from the Amami rabbit (Pentalagus furnessi) and evolutionally conserved cell cycle control with CDK4 and Cyclin D1. Biochem. Biophys. Res. Commun. 525 (4): 1046-1053 (2020). PMID 32178875.
          user_report Nishida, J., Epigenetic remodelling shapes inflammatory renal cancer and neutrophil-dependent metastasis. Nat. Cell Biol. 22 (4): 465-475 (2020). PMID 32203421.
          user_report Sasaki, K., Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity. Cell Rep. 31 (1): 107407 (2020). PMID 32268103.
          user_report Ma, J., gp96 Is Critical for both Human Herpesvirus 6A (HHV-6A) and HHV-6B Infection. J. Virol. 94 (13): e00311-20 (2020). PMID 32295911.
          user_report Aso, H., Multiomics Investigation Revealing the Characteristics of HIV-1-Infected Cells In Vivo. Cell Rep. 32 (2): 107887 (2020). PMID 32668246.
          user_report Kaibori, Y., Kinase activity-independent role of EphA2 in the regulation of M-phase progression. Exp. Cell Res. 395 (2): 112207 (2020). PMID 32750331.
          user_report Seki, R., Induced pluripotent stem cell-derived monocytic cell lines from a NOMID patient serve as a screening platform for modulating NLRP3 inflammasome activity. PLoS One 15 (8): e0237030 (2020). PMID 32810141.
          user_report Ito, S., Asbestos conceives Fe(II)-dependent mutagenic stromal milieu through ceaseless macrophage ferroptosis and beta-catenin induction in mesothelium. Redox Biology 36: 101616 (2020). PMID 32863225.
          user_report Kakizawa, S., Functional maintenance of calcium store by ShcB adaptor protein in cerebellar Purkinje cells. Sci. Rep. 10 (1): 14475 (2020). PMID 32879382.
          user_report Funato, Y., The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis. Dev. Cell S1534-5807 (20) 30667-5 (2020). PMID 32918875.
          user_report Han, N., Bromodomain-containing protein 4 regulates interleukin-34 expression in mouse ovarian cancer cells. Inflamm. Regen. 40: 25 (2020). PMID 33072227.
          user_report Ikeda, M., UBE1a Suppresses Herpes Simplex Virus-1 Replication. Viruses 12 (12): 1391 (2020). PMID 33291814.
          user_report Murayama, A.Y., The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets. Sci. Rep. 10 (1): 21516 (2020). PMID 33299078.
          user_report Ouwendijk, W.J.D., Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency. Nat. Commun. 11 (1): 6324 (2020). PMID 33303747.
          user_report Kakihana, A., Heat shock-induced mitotic arrest requires heat shock protein 105 for the activation of spindle assembly checkpoint. FASEB J. 33 (3): 3936-3953 (2019). PMID 30496702.
          user_report Nishimura, T., Cancer stem-like properties and gefitinib resistance are dependent on purine synthetic metabolism mediated by the mitochondrial enzyme MTHFD2. Oncogene 38 (14): 2464-2481 (2019). PMID 30532069.
          user_report Kaibori, Y., EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity. FASEB J. 33 (4): 5334-5349 (2019). PMID 30668924.
          user_report Echizen, K., NF-kappaB-induced NOX1 activation promotes gastric tumorigenesis through the expansion of SOX2-positive epithelial cells. Oncogene 38 (22): 4250-4263 (2019). PMID 30700829.
          user_report Ishibashi, D., Type I interferon protects neurons from prions in in vivo models. Brain 142 (4): 1035-1050 (2019). PMID 30753318.
          user_report Ito, T., Mathematical analysis of gefitinib resistance of lung adenocarcinoma caused by MET amplification. Biochem. Biophys. Res. Commun. 511 (3): 544-550 (2019). PMID 30824185.
          user_report Fujii, S., Wnt/beta-catenin signaling, which is activated in odontomas, reduces Sema3A expression to regulate odontogenic epithelial cell proliferation and tooth germ development. Sci. Rep. 9 (1): 4257 (2019). PMID 30862786.
          user_report Iwamoto, M., Epidermal growth factor receptor is a host-entry cofactor triggering hepatitis B virus internalization. Proc. Natl. Acad. Sci. U.S.A.116 (17): 8487-8492 (2019). PMID 30952782.
          user_report Makino, Y., Single cell RNA-sequencing identified Dec2 as a suppressive factor for spermatogonial differentiation by inhibiting Sohlh1 expression. Sci. Rep. 9 (1): 6063 (2019). PMID 30988352.
          user_report Hui, K.K., GABARAPs dysfunction by autophagy deficiency in adolescent brain impairs GABAA receptor trafficking and social behavior. Sci. Adv. 5 (4): eaau8237 (2019). PMID 30989111.
          user_report Kinoshita, N., Genetically Encoded Fluorescent Indicator GRAPHIC Delineates Intercellular Connections. iScience 15: 28-38 (2019). PMID 31026667.
          user_report Nakamura, H., Organoid culture containing cancer cells and stromal cells reveals that podoplanin-positive cancer-associated fibroblasts enhance proliferation of lung cancer cells. Lung Cancer 134: 100-107 (2019). PMID 31319967.
          user_report Suzuki, E., Secretion of high amounts of hepatocyte growth factor is a characteristic feature of cancer-associated fibroblasts with EGFR-TKI resistance-promoting phenotype: A study of 18 cases of cancer-associated fibroblasts. Pathol. Int. 69 (8): 472-480 (2019). PMID 31339210.
          user_report Kawasaki, Y., he novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis. EMBO Rep. 20 (8): e47052 (2019). PMID 31353791.
          user_report Tani, T., Establishment of immortalized primary cell from the critically endangered Bonin flying fox (Pteropus pselaphon). PLoS One 14 (8): e0221364 (2019). PMID 31449544.
          user_report Matsumoto, S., GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFbeta signaling. Nat. Commun. 10(1): 3882 (2019). PMID 31462641.
          user_report Mitani, A., Characterization of doxycycline-dependent inducible Simian Virus 40 large T antigen immortalized human conjunctival epithelial cell line. PLoS One 14 (9): e0222454 (2019). PMID 31509592.
          user_report Fujimoto, S., KLF4 prevents epithelial to mesenchymal transition in human corneal epithelial cells via endogenous TGF-beta2 suppression. Regen. Ther. 11: 249-257 (2019). PMID 31538102.
          user_report Watanabe, N., A pull-down and slot blot-based screening system for inhibitor compounds of the podoplanin-CLEC-2 interaction. PLoS One 14 (9): e0222331 (2019). PMID 31553741.
          user_report Yamagishi, M., Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas. Cell Rep. 29 (8): 2321-2337.e7 (2019). PMID 31747604.
          user_report Takahashi, S., Loss of p57 KIP2 expression confers resistance to contact inhibition in human androgenetic trophoblast stem cells. Proc. Natl. Acad. Sci. U.S.A. pii: 201916019 (2019). PMID 31792181.
          user_report Inoue, S., Uterine adenomyosis is an oligoclonal disorder associated with KRAS mutations. Nat. Commun. 10 (1): 5785 (2019). PMID 31857578.
          user_report Sasaki, M., Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assay. Virus Res. 243: 69-74 (2018). PMID 29074234.
          user_report Takahashi, Y., A Refined Culture System for Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Organoids. Stem Cell Reports 10 (1): 314-328 (2018). PMID 29233552.
          user_report Kanaya, T., Development of intestinal M cells and follicle-associated epithelium is regulated by TRAF6-mediated NF-κB signaling. J. Exp. Med. 215 (2): 501-519 (2018). PMID 29339448.
          user_report Kovačević. I., The Cullin-3-Rbx1-KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB. J. Cell Biol. 217 (3): 1015-1032 (2018). PMID 29358211.
          user_report Fukuda, T., The poly-cistronic expression of four transcriptional factors (CRX, RAX, NEURO-D, OTX2) in fibroblasts via retro- or lentivirus causes partial reprogramming into photoreceptor cells. Cell Biol. Int. 42 (5): 608-614 (2018). PMID 29377330.
          user_report Kawasaki, N., TUFT1 interacts with RABGAP1 and regulates mTORC1 signaling Cell Discovery 4 (1): (2018). PMID 29423269.
          user_report Hiyama, N., Glutamate-cysteine ligase catalytic subunit is associated with cisplatin resistance in lung adenocarcinoma. Jpn. J. Clin. Oncol. 48 (4): 303-307 (2018). PMID 29474642.
          user_report Fujita, T., enChIP systems using different CRISPR orthologues and epitope tags. BMC Res. Notes 11 (1): 154 (2018). PMID 29482606.
          user_report Oda, T., Acute HSF1 depletion induces cellular senescence through the MDM2-p53-p21 pathway in human diploid fibroblasts. J. Cell Sci. 131 (9). pii: jcs210724 (2018). PMID 29632240.
          user_report Endo, R., TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration. Biol. Psychiatry. 84(7): 509-521 (2018). PMID 29752072.
          user_report Yamamura, H., Hypoxic stress up-regulates Kir2.1 expression by a pathway including hypoxic-inducible factor-1 and dynamin2 in brain capillary endothelial cells. Am. J. Physiol. Cell Physiol. 315 (2): C202-C213 (2018). PMID 29768048.
          user_report Ueda, N., Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response. Stem Cell Reports 10 (6): 1935-1946 (2018). PMID 29805109.
          user_report Uenaka, T., In silico drug screening by using genome-wide association study data repurposed dabrafenib, an anti-melanoma drug, for Parkinson's disease. Hum. Mol. Genet. 27 (22): 3974-3985 (2018). PMID 30137437.
          user_report Shamoto, N., CFAP70 Is a Novel Axoneme-Binding Protein That Localizes at the Base of the Outer Dynein Arm and Regulates Ciliary Motility. Cells 7 (9). pii: E124 (2018). PMID 30158508.
          user_report Mochizuki, K., Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination. Cell Rep. 24 (10): 2682-2693.e6 (2018). PMID 30184502.
          user_report Funato, K., SIRT2-mediated inactivation of p73 is required for glioblastoma tumorigenicity. EMBO Rep. 19 (11). pii: e45587 (2018). PMID 30213795.
          user_report Gouko, R., Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant CDK4, Cyclin D1, and telomerase reverse transcriptase. Cytotechnology 70 (6): 1619-1630 (2018). PMID 30225752.
          user_report Tanaka, K., Role of leukotriene B4 12-hydroxydehydrogenase in α-galactosylceramide-pulsed dendritic cell therapy for non-small cell lung cancer. Biochem. Biophys. Res. Commun. 506 (1): 27-32 (2018). PMID 30336981.
          user_report Takahashi, M., USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis. iScience 9: 433-450. (2018). PMID 30469013.
          user_report Fukuda, T., Expression of Six Proteins Causes Reprogramming of Porcine Fibroblasts into Induced Pluripotent Stem Cells with Both Active X Chromosomes. J. Cell Biochem. 118(3): 537-553 (2017). PMID 27608441.
          user_report Kishimoto, W., Expression of Tim-1 in primary CNS lymphoma. Cancer Med. 5 (11): 3235-3245 (2017). PMID 27709813.
          user_report Suzuki, S., Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons. Biochem. Biophys. Res. Commun. 483 (1): 88-93 (2017). PMID 28057485.
          user_report Kuroda,, miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway. BMC Cancer 17 (1): 33 (2017). PMID 28061765.
          user_report Mikami, H., Requirement of Hsp105 in CoCl2-induced HIF-1α accumulation and transcriptional activation. Exp. Cell Res. 352 (2): 225-233 (2017). PMID 28185835.
          user_report Inagaki, S., Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging. Sci. Rep. 7: 42398 (2017). PMID 28205521.
          user_report Tanaka, M., Aggregation of scaffolding protein DISC1 dysregulates phosphodiesterase 4 in Huntington's disease. J. Clin. Invest. \127 (4): 1438-1450 (2017). PMID 28263187.
          user_report Katayama, M., Immortalized prairie vole-derived fibroblasts (VMF-K4DTs) can be transformed into pluripotent stem cells and provide a useful tool with which to determine optimal reprogramming conditions. J. Reprod. Dev. 63 (3): 311-318 (2017). PMID 28331164.
          user_report Ueno, N., PU.1 acts as tumor suppressor for myeloma cells through direct transcriptional repression of IRF4. Oncogene 36 (31): 4481-4497 (2017). PMID 28368411.
          user_report Tomioka, I., Transgenic Monkey Model of the Polyglutamine Diseases Recapitulating Progressive Neurological Symptoms. eNeuro 4 (2). pii: ENEURO.0250-16 (2017). PMID 28374014.
          user_report Goyal, S., RUNX1 induces DNA replication independent active DNA demethylation at SPI1 regulatory regions BMC Mol. Biol. 18 (1): 9 (2017). PMID 28376714.
          user_report Ishibashi, M., CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors. Sci. Rep. 7: 46662 (2017). PMID 28429795.
          user_report Shimokawa, C., Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections. Immunity 46 (5): 863-874 (2017). PMID 28514691.
          user_report Katsura, A., ZEB1-regulated inflammatory phenotype in breast cancer cells. Mol. Oncol. 11 (9): 1241-1262 (2017). PMID 28618162.
          user_report Kubota, S.I., Whole-Body Profiling of Cancer Metastasis with Single-Cell Resolution. Cell Rep. 20 (1): 236-250 (2017). PMID 28683317.
          user_report Yamamoto, E., Establishment and characterization of cell lines derived from complete hydatidiform mole. Int. J. Mol. Med. 40 (3): 614-622 (2017). PMID 28713902.
          user_report Watanabe, N., A cell-based high-throughput screening assay system for inhibitor compounds of antigen presentation by HLA class II molecule. Sci. Rep. 7 (1): 6798 (2017). PMID 28754892.
          user_report Yanagihashi, Y., Mouse macrophages show different requirements for phosphatidylserine receptor Tim4 in efferocytosis. Proc. Natl. Acad. Sci. U.S.A. 114 (33): 8800-8805 (2017). PMID 28768810.
          user_report Takahashi, Y., Reciprocal Inflammatory Signaling Between Intestinal Epithelial Cells and Adipocytes in the Absence of Immune Cells. EBioMedicine. 23: 34-45 (2017). PMID 28789943.
          user_report Ito, N., Direct reprogramming of fibroblasts into skeletal muscle progenitor cells by transcription factors enriched in undifferentiated subpopulation of satellite cells. Sci. Rep. 7 (1): 8097 (2017). PMID 28808339.
          user_report Quach, H.T., Eudesmane-Type Sesquiterpene Lactones Inhibit Nuclear Translocation of the Nuclear Factor kappaB Subunit RelB in Response to a Lymphotoxin beta Stimulation. Biol. Pharm. Bull. 40 (10): 1669-1677 (2017). PMID 28966239.
          user_report Nakatsumi, H., Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages. Cell Rep. 21 (9): 2471-2486 (2017). PMID 29186685.
          user_report Nakamori, D., Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction. Sci. Rep. 7 (1): 16675 (2017). PMID 29192290.
          user_report Hirano, K., FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1. FEBS Open Bio. 7 (12): 1932-1942 (2017). PMID 29226080.
          user_report Fuchigami, T., Fibroblasts promote the collective invasion of ameloblastoma tumor cells in a 3D coculture model. FEBS Open Bio. 7 (12): 2000-2007 (2017). PMID 29226086.
          user_report Kobayashi, S., TGF-beta induces the differentiation of human CXCL13-producing CD4(+) T cells. Eur. J. Immunol. 46 (2): 360-371 (2016). PMID 26541894.
          user_report Katsura, A., MicroRNA-31 is a positive modulator of endothelial-mesenchymal transition and associated secretory phenotype induced by TGF-beta. Genes Cells 21 (1): 99-116 PMID 26663584.
          user_report Ujino, S., Hepatitis C virus utilizes VLDLR as a novel entry pathway. Proc. Natl. Acad. Sci. U.S.A. 113 (1): 188-193 (2016). PMID 26699506.
          user_report , PMID 26768845.
          user_report Kobayashi, S., Rab8b Regulates Transport of West Nile Virus Particles from Recycling Endosomes. J. Biol. Chem. 291 (12): 6559-6568 (2016). PMID 26817838.
          user_report Fukuda, S., Reversible interconversion and maintenance of mammary epithelial cell characteristics by the ligand-regulated EGFR system. Sci. Rep. 6: 20209 (2016). PMID 26831618.
          user_report Sasamoto, Y., PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes. Sci. Rep. 6: 20807, 2016. PMID 26899008.
          user_report Kobayashi, M., Functional Analysis of Novel Candidate Regulators of Insulin Secretion in the MIN6 Mouse Pancreatic beta Cell Line PLoS One 11 (3): e0151927 (2016). PMID 26986842.
          user_report Hirano, K., LSD1 Mediates Neuronal Differentiation of Human Fetal Neural Stem Cells by Controlling The Expression of a Novel Target Gene, HEYL. Stem Cells 34 (7): 1872-1882 (2016). PMID 27018646.
          user_report Imamura, Y., Generation of Large Numbers of Antigen-Expressing Human Dendritic Cells Using CD14-ML Technology. PLoS One. 2016 Apr 6;11(4):e0152384 (2016). PMID 27050553.
          user_report Maishi, N., Tumour endothelial cells in high metastatic tumours promote metastasis via epigenetic dysregulation of biglycan. Sci. Rep. 6: 28039 (2016). PMID 27295191.
          user_report Kimura, H., CKAP4 is a Dickkopf1 receptor and is involved in tumor progression. J. Clin. Invest. 126 (7): 2689-2705 (2016). PMID 27322059.
          user_report Kuo, K.K., Positive Feedback Loop of OCT4 and c-JUN Expedites Cancer Stemness in Liver Cancer. Stem Cells 34 (11): 2613-2624 (2016). PMID 27341307.
          user_report Meitinger, F., 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J. Cell Biol. 214 (2): 155-166 (2016). PMID 27432897.
          user_report Fukuda, T., Cellular conservation of endangered midget buffalo (Lowland Anoa, Bubalus quarlesi) by establishment of primary cultured cell, and its immortalization with expression of cell cycle regulators. Cytotechnology 68 (5): 1937-1947 (2016). PMID 27449922.
          user_report Suzuki, K., MEF2D-BCL9 Fusion Gene Is Associated With High-Risk Acute B-Cell Precursor Lymphoblastic Leukemia in Adolescents. J. Clin. Oncol. 34 (28): 3451-3459 (2016). PMID 27507882.
          user_report Uezumi, A., Cell-Surface Protein Profiling Identifies Distinctive Markers of Progenitor Cells in Human Skeletal Muscle. Stem Cell Reports 7 (2): 263-278 (2016). PMID 27509136 .
          user_report Sakane, A., Conformational plasticity of JRAB/MICAL-L2 provides 'law and order' in collective cell migration. Mol. Biol. Cell 27(20): 3095-3108 (2016). PMID 27582384.
          user_report Iborra, S., Leishmania Uses Mincle to Target an Inhibitory ITAM Signaling Pathway in Dendritic Cells that Dampens Adaptive Immunity to Infection. Immunity 45 (4): 788-801 (2016). PMID 27742545.
          user_report Taniue, K., ASBEL-TCF3 complex is required for the tumorigenicity of colorectal cancer cells. Proc. Natl. Acad. Sci. U.S.A. 113 (45): 12739–12744 (2016). PMID 27791078.
          user_report Higuchi, M., USP10 Is an Essential Deubiquitinase for Hematopoiesis and Inhibits Apoptosis of Long-Term Hematopoietic Stem Cells. Stem Cell Reports 7 (6): 1116-1129 (2016). PMID 27974222.
          user_report Hanawa, M., Hepatocyte Nuclear Factor 4 Alpha Promotes Definitive Endoderm Differentiation from Human Induced Pluripotent Stem Cells. Stem Cell Rev. 13 (4): 542-551 (2017). PMID 28000155.
          user_report Matsuda, Y., Epigenetic Heterogeneity in HIV-1 Latency Establishment. Sci. Rep. 5: 7701 (2015). PMID 25572573.
          user_report Neri, S., Podoplanin-expressing cancer-associated fibroblasts lead and enhance the local invasion of cancer cells in lung adenocarcinoma. Int. J. Cancer. 137 (4): 784-796 (2015). PMID 25648219.
          user_report Nakatani, T., Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced gammaH2AX accumulation. EMBO Rep. 16 (5): 582-9 (2015). PMID 25694116.
          user_report Kusakari, S., Shp2 in forebrain neurons regulates synaptic plasticity, locomotion, and memory formation in mice. Mol. Cell. Biol. 35 (9): 1557-1572 (2015). PMID 25713104.
          user_report Katsuhara, A., Transduction of a novel HLA-DRB1*04:05-restricted, WT1-specific TCR gene into human CD4+ T cells confers killing activity against human leukemia cells. Anticancer Res. 35 (3): 1251-1261 (2015). PMID 25750272.
          user_report Hiraoka, K., SOX9-mediated upregulation of LGR5 is important for glioblastoma tumorigenicity. Biochem. Biophys. Res. Commun. 460 (2): 216-221 (2015). PMID 25770425.
          user_report Hikita, A., Analyses of bone modeling and remodeling using in vitro reconstitution system with two-photon microscopy. Bone 76: 5-17 (2015). PMID 25771421.
          user_report Saito, M., 3beta-hydroxysterol delta24-reductase on the surface of hepatitis C virus-related hepatocellular carcinoma cells can be a target for molecular targeting therapy. PLoS One 10 (4): e0124197 (2015). PMID 25875901.
          user_report Ibuka, S., The P2Y2 receptor promotes Wnt3a- and EGF-induced epithelial tubular formation by IEC6 cells by binding to integrins. J. Cell Sci. 128 (11): 2156-2168 (2015). PMID 25908848.
          user_report Hashizume, O., Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects. Sci. Rep. 5: 10434 (2015). PMID 26000717.
          user_report Hira, A., Mutations in the Gene Encoding the E2 Conjugating Enzyme UBE2T Cause Fanconi Anemia. Am. J. Hum. Genet. 96 (6): 1001-1007 (2015). PMID 26046368.
          user_report Minamino, M., Esco1 Acetylates Cohesin via a Mechanism Different from That of Esco2. Curr. Biol. 25 (13): 1694-1706 (2015). PMID 26051894.
          user_report Tsuyama, J., MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells. Stem Cell Reports 5 (3): 365-377 (2015). PMID 26212661.
          user_report Shimojo, D., Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells. Mol. Brain. 8 (1): 79 (2015). PMID 26626025.
          user_report Koyama-Nasu, R., The pleiotrophin-ALK axis is required for tumorigenicity of glioblastoma stem cells. Oncogene, 33 (17): 2236-2244 (2014). PMID 23686309.
          user_report Uemura, S., Expression machinery of GM4: the excess amounts of GM3/GM4S synthase (ST3GAL5) are necessary for GM4 synthesis in mammalian cells. Glycoconj. J. 31 (2): 101-108 (2014). PMID 23999868.
          user_report Ohnishi, T., Identification and characterization of a neuron-specific isoform of protrudin. Genes Cells 19 (2): 97-111 (2014). PMID 24251978.
          user_report Ito, R., TET3-OGT interaction increases the stability and the presence of OGT in chromatin. Genes Cells, 19 (1): 52-65 (2014). PMID 24304661.
          user_report Ishikawa, F., A mitochondrial thioredoxin-sensitive mechanism regulates TGF-beta-mediated gene expression associated with epithelial-mesenchymal transition. Biochem. Biophys. Res. Commun., pii: S0006-291X (13) 02109-8 (2014). PMID 24342608.
          user_report Tsuji, S., The miR-363-GATA6-Lgr5 pathway is critical for colorectal tumourigenesis. Nat. Commun., 5: 3150 (2014). PMID 24452072.
          user_report Matsumoto, S., A combination of Wnt and growth factor signaling induces Arl4c expression to form epithelial tubular structures. EMBO J., 33 (7): 702-718 (2014). PMID 24562386.
          user_report Donai, K., Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase. J. Biotechnol., 176: 50-57 (2014). PMID 24589663.
          user_report Chapnick, D.A., Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets. Mol. Biol. Cell, 25 (10): 1586-1593 (2014). PMID 24623725.
          user_report Zhou, Z., Reprogramming non-human primate somatic cells into functional neuronal cells by defined factors. Mol. Brain, 7: 24 (2014). PMID 24694048.
          user_report Hirokawa, T., CBP-93872 inhibits NBS1-mediated ATR activation, abrogating maintenance of the DNA double-strand break-specific G2 checkpoint. Cancer Res. 74 (14): 3880-3889 (2014). PMID 24876101.
          user_report Muraoka, N., MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures. EMBO J., 33 (14): 1565-1581 (2014). PMID 24920580.
          user_report Yu, F.X., Construction of a lentiviral T/A vector for direct analysis of PCR-amplified promoters. Mol. Biol. Rep. 41 (11): 7651-7658 (2014). PMID 25091945.
          user_report Higuchi, M., Downregulation of proapoptotic Bim augments IL-2-independent T-cell transformation by human T-cell leukemia virus type-1 Tax. Cancer Med. 3 (6): 1605-1614 (2014). PMID 25175936.
          user_report Koyama-Nasu, R., The critical role of cyclin D2 in cell cycle progression and tumorigenicity of glioblastoma stem cells. Oncogene, 32 (33): 3840-3845 (2013). PMID 22964630.
          user_report Takayama, G., Class I PI3K-mediated Akt and ERK signals play a critical role in Fc{varepsilon}RI-induced degranulation in mast cells. Int. Immunol., 25 (4): 215-220 (2013). PMID 23143475.
          user_report Shibukawa, Y., Rock-dependent calponin 3 phosphorylation regulates myoblast fusion. Exp. Cell Res., 319 (5): 633-648 (2013). PMID 23276748.
          user_report Ishibashi, M., Clinical significance of the expression of long non-coding RNA HOTAIR in primary hepatocellular carcinoma. Oncol. Rep. 29 (3): 946-950 (2013). PMID 23292722.
          user_report Koyama-Nasu, R, The cancer stem cell marker CD133 interacts with plakoglobin and controls desmoglein-2 protein levels. PLoS One, 8 (1): e53710 (2013). PMID 23326490.
          user_report Suzuki, S., Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro. Biochem. Biophys. Res. Commun., 432 (1): 92-98 (2013). PMID 23376076.
          user_report Kurosawa, N., Reduced level of the BCL11B protein is associated with adult T-cell leukemia/lymphoma. PLoS One, 8 (1): e55147 (2013). PMID 23383087.
          user_report Yanagida, S., ASBEL, an ANA/BTG3 antisense transcript required for tumorigenicity of ovarian carcinoma. Sci Rep. 2013 Feb 19;3:1305 PMID 23419616.
          user_report Daimon, E., Calponin 3 regulates stress fiber formation in dermal fibroblasts during wound healing. Arch. Dermatol. Res., 305 (7): 571-584 (2013). PMID 23545751.
          user_report Nanba, D., Actin filament dynamics impacts keratinocyte stem cell maintenance. EMBO Mol Med., 5 (4): 640-653 (2013). PMID 23554171.
          user_report Matsushita, N., Doxycycline-dependent inducible and reversible RNA interference mediated by a single lentivirus vector. Biosci. Biotechnol. Biochem., 77 (4): 776-781 (2013). PMID 23563548.
          user_report Moriyama, H., Tightly regulated and homogeneous transgene expression in human adipose-derived mesenchymal stem cells by lentivirus with tet-off system. PLoS One, 8 (6): e66274 (2013). PMID 23776652.
          user_report Takahashi, Y., Paired related homoeobox 1, a new EMT inducer, is involved in metastasis and poor prognosis in colorectal cancer. Br. J. Cancer, 109 (2): 307-311 (2013). PMID 23807160.
          user_report Sereti, K.I., Methods to study the proliferation and differentiation of cardiac side population (CSP) cells. Methods Mol. Biol. 1036: 95-106 (2013). PMID 23807790.
          user_report Koba, C., Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-beta against peritoneally disseminated cancer in xenograft models. PLoS One, 8 (6): e67567 (2013). PMID 23826321.
          user_report Donai, K., Establishment of a reporter system to monitor silencing status in induced pluripotent stem cell lines. Anal. Biochem. 443 (1): 104-112 (2013). PMID 23973628.
          user_report Yugawa, T., Noncanonical NOTCH signaling limits self-renewal of human epithelial and induced pluripotent stem cells through ROCK activation. Mol. Cell. Biol., 233 (22): 4434-4447 (2013). PMID 24019071.
          user_report Uchi, R., PICT1 regulates TP53 via RPL11 and is involved in gastric cancer progression. Br. J. Cancer, 109 (8): 2199-2206 (2013). PMID 24045667.
          user_report Sasaki, R., Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes. Carcinogenesis, 30 (3): 423-431 (2012). PMID 19126650.
          user_report Kobayashi, K., Oct-3/4 promotes migration and invasion of glioblastoma cells. J. Cell Biochem., 113 (2): 508-517 (2012). PMID 21938739.
          user_report Yoshita, M., Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth. Cancer Sci., 103 (2): 369-374 (2012). PMID 22010857.
          user_report Shikata, H., Role of activation-induced cytidine deaminase in the progression of follicular lymphoma. Cancer Sci. 103 (3): 415-421 (2012). PMID 22168746.
          user_report Toyomitsu, E., CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia. Purinergic Signal., 8 (2): 301-310 (2012). PMID 22222817.
          user_report Yamagishi M, Polycomb-Mediated Loss of miR-31 Activates NIK-Dependent NF-κB Pathway in Adult T Cell Leukemia and Other Cancers. Cancer Cell, 21 (1): 121-135 (2012). PMID 22264793.
          user_report Suzuki, M., Live-cell imaging visualizes frequent mitotic skipping during senescence-like growth arrest in mammary carcinoma cells exposed to ionizing radiation. Int. J. Radiat. Oncol. Biol. Phys., 83 (2): e241-250 (2012). PMID 22365624.
          user_report Watanabe, T., FBL2 regulates amyloid precursor protein (APP) metabolism by promoting ubiquitination-dependent APP degradation and inhibition of APP endocytosis. J. Neurosci., 32 (10): 3352-3365 (2012). PMID 22399757.
          user_report Suzuki, T.,, Reconstruction of monocyte transcriptional regulatory network accompanies monocytic functions in human fibroblasts. PLoS One, 7 (3): e33474 (2012). PMID 22428058.
          user_report Maruyama, T., Hypothermia-induced tyrosine phosphorylation of SIRP alpha in the brain. J. Neurochem., 121 (6): 891-902 (2012). PMID 22468987.
          user_report Hirota, Y., Roles of planar cell polarity signaling in maturation of neuronal precursor cells in the postnatal mouse olfactory bulb. Stem Cells, 30 (8): 1726-1733 (2012).無 PMID 22628050.
          user_report Masuda, T., IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype. Cell Rep., 1 (4): 334-340 (2012). PMID 22832225.
          user_report Makino, K., Discoidin domain receptor 2-microRNA 196a-mediated negative feedback against excess type I collagen expression is impaired in scleroderma dermal fibroblasts. J. Invest. Dermatol., 133 (1): 110-119 (2012). PMID 22832484.
          user_report Moriyama, M., Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling. BMC Cell Biol. 2012 Aug 7;13:21 (2012). PMID 22870983.
          user_report Imai, M., Human T cell leukemia virus type 2 (HTLV-2) Tax2 has a dominant activity over HTLV-1 Tax1 to immortalize human CD4(+) T cells. Virus Genes, 46 (1): 39-46 (2012). PMID 23054433.
          user_report Hasegawa, K., Retinoic acid signaling in Sertoli cells regulates organization of the blood-testis barrier through cyclical changes in gene expression. Development, 139 (23): 4347-4355 (2012). PMID 23095883.
          user_report Makinoshima, H., PTPRZ1 regulates calmodulin phosphorylation and tumor progression in small-cell lung carcinoma. BMC Cancer, 12: 537 (2012). PMID 23170925.
          user_report Jounai, N., NLRP4 negatively regulates autophagic processes through an association with Beclin1. J. Immunol., 186 (3): 1646-1655 (2011). PMID 21209283.
          user_report Sakaue-Sawano, A., Drug-induced cell cycle modulation leading to cell-cycle arrest, nuclear mis-segregation, or endoreplication. BMC Cell Biol. 12: 2 (2011). PMID 21226962.
          user_report Amako, Y., Protein kinase D negatively regulates hepatitis C virus secretion through phosphorylation of oxysterol-binding protein and ceramide transfer protein. J. Biol. Chem., 286 (13): 11265-11274 (2011). PMID 21285358.
          user_report Sasaki, M., Equine major histocompatibility complex class I molecules act as entry receptors that bind to equine herpesvirus-1 glycoprotein D. Genes Cells, 16 (4), 343-357 (2011). PMID 21306483.
          user_report Fujita, K., Effects of a brain-engraftable microglial cell line expressing anti-prion scFv antibodies on survival times of mice infected with scrapie prions. Cell. Mol. Neurobiol. 31 (7): 999-1008 (2011). PMID 21516351.
          user_report Kataoka, A., Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways. Purinerg. Signal, 7 (4): 403-411 (2011). PMID 21567128.
          user_report Yamashita, D., MCPH1 regulates chromosome condensation and shaping as a composite modulator of condensin II. J. Cell Biol. 194 (6): 841-854 (2011). PMID 21911480.
          user_report Tanaka, Y., Dual Function of Histone H3 Lysine 36 Methyltransferase ASH1 in Regulation of Hox Gene Expression. PLoS One., 6 (11): e28171 (2011). PMID 22140534.
          user_report Aoyagi T., The PDZ domain binding motif (PBM) of human T-cell leukemia virus type 1 Tax can be substituted by heterologous PBMs from viral oncoproteins during T-cell transformation. Virus Genes., 40, 193-199 (2010). PMID 20069350.
          user_report Takeda, H., Activation of epidermal growth factor receptor gene is involved in transforming growth factor-beta-mediated fibronectin expression in a chondrocyte progenitor cell line. Int. J. Mol. Med., 25 (4): 593-600 (2010). PMID 20198308.
          user_report Sumimoto, H., The RNA silencing technology applied by lentiviral vectors in oncology. Methods Mol. Biol., 614, 1-87-199 (2010). PMID 20225045.
          user_report Koizumi T., Depletion of Dnmt1-associated protein 1 triggers DNA damage and compromises the proliferative capacity of hematopoietic stem cells. Int. J. Hematol., 91, 611-619 (2010). PMID 20387133.
          user_report Nishie T., Beta4-galactosyltransferase-5 is a lactosylceramide synthase essential for mouse extra-embryonic development. Glycobiology., 20, 1311-1322 (2010). PMID 20574042.
          user_report Tsuji O., Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc. Natl. Acad. Sci. USA., 107, 12704-12709 (2010). PMID 20615974.
          user_report Honda A., Generation of induced pluripotent stem cells in rabbits: potential experimental models for human regenerative medicine. J. Biol. Chem., 285, 31362-31369 (2010). PMID 20670936.
          user_report Matsuda, S., Critical role of class IA PI3K for c-Rel expression in B lymphocytes. Blood., 113, 1037-1044 (2009). PMID 18927440.
          user_report Inuzuka T., Transcription factor 8 activates R-Ras to regulate angiogenesis. Biochem. Biophys. Res. Commun., 379, 510-513 (2009). PMID 19116136.
          user_report Fukushima K., FIP1L1-PDGFRalpha imposes eosinophil lineage commitment on hematopoietic stem/progenitor cells. J. Biol. Chem., 284, 7719-7732 (2009). PMID 19147501.
          user_report Isaji T., N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: identification of the minimal N-glycosylation requirement for alpha5beta1. J. Biol. Chem., 284, 12207-12216 (2009). PMID 19261610.
          user_report Ohoka, N., The orphan nuclear receptor RORalpha restrains adipocyte differentiation through a reduction of C/EBPbeta activity and perilipin gene expression. Mol. Endocrinol., 23, 759-771 (2009). PMID 19324970.
          user_report Shinoda Y., Efficient transduction of cytotoxic and anti-HIV-1 genes by a gene-regulatable lentiviral vector. Virus Genes., 39, 165-175 (2009). PMID 19554442.
          user_report Miura K., Variation in the safety of induced pluripotent stem cell lines. Nat. Biotechnol., 27, 743-745 (2009). PMID 19590502.
          user_report Kanemura H., Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1. Biochem. Biophys. Res. Commun., 387, 754-759 (2009). PMID 19635461.
          user_report Kido K., Simultaneous suppression of MITF and BRAF V600E enhanced inhibition of melanoma cell proliferation. Cancer Sci., 100, 1863-1869 (2009). PMID 19659611.
          user_report Hanyu, A., Functional in vivo optical imaging of tumor angiogenesis, growth, and metastasis prevented by administration of anti-human VEGF antibody in xenograft model of human fibrosarcoma HT1080 cells. Cancer Sci. 100 (11): 2085-2092 (2009). PMID 19719773.
          user_report Shoji, T., Identification of a novel motif responsible for the distinctive transforming activity of human T-cell leukemia virus (HTLV) type 1 Tax1 protein from HTLV-2 Tax2. Retrovirology, 6: 83 (2009). PMID 19761585.
          user_report Sakai, T., Distinctive cell properties of B cells carrying the BCL2 translocation and their potential roles in the development of lymphoma of germinal center type. Cancer Sci. 100 (12): 2361-2367 (2009). PMID 19780757.
          user_report Miyake, Y., RPA-like mammalian Ctc1-Stn1-Ten1 complex binds to single-stranded DNA and protects telomeres independently of the Pot1 pathway. Mol. Cell 36 (2):193-206 (2009). PMID 19854130.
          user_report Isogawa, M., Rearranged NF-kappa B2 gene in an adult T-cell leukemia cell line. Cancer Sci., 99 (4): 792-798 (2008). PMID 18377428.
          user_report Yoshida, S., Knockdown of synapse-associated protein Dlg1 reduces syncytium formation induced by human T-cell leukemia virus type 1. Virus Genes, 37 (1): 9-15 (2008). PMID 18461433.
          user_report Inoue-Narita, T., Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res. 2008 Jul 15;68(14):5760-8 (2008). PMID 18632629.
          user_report Harao M., HLA-A2-restricted CTL epitopes of a novel lung cancer-associated cancer testis antigen, cell division cycle associated 1, can induce tumor-reactive CTL. Int. J. Cancer., 123, 2616-2625 (2008). PMID 18770861.
          user_report Imai K., Identification of a novel tumor-associated antigen, cadherin 3/P-cadherin, as a possible target for immunotherapy of pancreatic, gastric, and colorectal cancers. Clin. Cancer. Res., 14, 6487-6495 (2008). PMID 18927288.
          user_report Naka, H., Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat. Neurosci. 11 (9): 1014-1023 (2008). PMID 19160499.
          user_report Ehata, S., Ki26894, a novel transforming growth factor-beta type I receptor kinase inhibitor, inhibits in vitro invasion and in vivo bone metastasis of a human breast cancer cell line. Cancer Sci. 98 (1): 127-133 (2007). PMID 17129361.
          user_report Fumoto, T., Orphan nuclear receptor Nur77 accelerates the initial phase of adipocyte differentiation in 3T3-L1 cells by promoting mitotic clonal expansion. J. Biochem. 141 (2): 181-192 (2007). PMID 17167038.
          user_report Higuchi, M., Cooperation of NF-kappaB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell line. J. Virol. 81 (21): 11900-11907 (2007). PMID 17715223.
          user_report Tsukamoto H., TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4+ T cell clone. Eur. J. Immunol., 36, 1926-1937 (2006). PMID 16791876.
          user_report Irie A., Protein kinase D2 contributes to either IL-2 promoter regulation or induction of cell death upon TCR stimulation depending on its activity in Jurkat cells. Int. Immunol., 18, 1737-1747 (2006). PMID 17077180.

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