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hTRAIL/pMKITneo

Expression vector containing entire coding region of human TRAIL cDNA

Catalog number RDB02934
Resource name hTRAIL/pMKITneo
Alternative name human TRAIL cDNA
Clone info. Expression vector containing entire coding region of human TRAIL cDNA.
Vector backbone pMKITneo (Plasmid)
Size of vector backbone 5,800 bp
Selectable markers Amp^r (E. coli), Neo (Mammalian cell)
Gene/insert name Human Apo-2L/TRAIL/TNFSF10 cDNA
Depositor|Developer Yagita, Hideo |
Other clones in our bank
External Database
Human Apo-2L/TRAIL/TNFSF10
          Reference sequence
            
           

          Distribution information

          Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
          Terms and conditions for distribution In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature(s) designated by the DEPOSITOR is requested (Kayagaki et al., J. Immunol., 162, 2639-2647, 1999).
          Ordering Please visit Information of Request for Distribution.[link] For for-profit-research purpose, please contact us. 
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          Material Transfer Agreement (MTA for use for not-for-profit academic purpose) [Word]
          提供案内 (日本国内) [open/close]

          提供条件 利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する (Kayagaki et al., J. Immunol., 162, 2639-2647, 1999)。
          提供依頼 手続きの詳細は、「提供申込みについて[link]」をご覧ください。営利目的利用についてはお問い合わせください。
          提供依頼書 [Word]
          提供同意書 (MTA、非営利機関による非営利学術研究用)[Word]

          Catalog # Resource name Availability Shipping form Fee (non-profit org.)
          RDB02934 hTRAIL/pMKITneo Under QC test. Please contact us. DNA solution Please contact us.

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          How to cite this biological resource

          Materials & Methods section:

          The hTRAIL/pMKITneo was provided by the RIKEN BRC through the National BioResource Project of the MEXT, Japan (cat. RDB02934).

          Reference section:

          , Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity. J. Immunol., 162, 2639-2647 (1999). PMID 10072506.
          , Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J. Immunol., 163, 1906-1913 (1999). PMID 10438925.

          Further references such as user reports and related articles (go to bottom)

          References and tips

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          QC test results

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          References

          Original, user report and related articles

          original , Involvement of TNF-related apoptosis-inducing ligand in human CD4+ T cell-mediated cytotoxicity. J. Immunol., 162, 2639-2647 (1999). PMID 10072506.
          original , Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J. Immunol., 163, 1906-1913 (1999). PMID 10438925.
          user_report Pennati, M., YM155 sensitizes triple-negative breast cancer to membrane-bound TRAIL through p38 MAPK- and CHOP-mediated DR5 upregulation. Int. J. Cancer 136 (2): 299-309 (2015). PMID 24866585 .
          user_report Rossini, A., Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34⁺ cells in a xenograft model. Breast Cancer Res. Treat., 136 (2): 457-467 (2012). PMID 23053664.
          user_report Lavazza, C., Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature. Blood, 115 (11), 2231-2240 (2010). PMID 20075160.

          2023.05.02

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