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AxCAZ3-F/RGD

Recombinant adenovirus expressing E. coli lacZ. Fiber-mutant, F/RGD

Catalog number RDB02194
Resource name AxCAZ3-F/RGD
Clone info. Recombinant adenovirus (type 5) expressing E. coli lacZ regulated by CAG promoter. Fiber-mutant, F/RGD.
Vector backbone Adenovirus
Size of vector backbone -
Growth remarks 5 percent FCS is fine.
Gene/insert name E. coli lacZ (beta-D-galactosidase) Genomic DNA
Depositor|Developer Hamada, Hirofumi |
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External Database
E. coli lacZ (beta-D-galactosidase)
          Reference sequence
            
           
          Remarks, protocol and/or map (gif) RDB02194.gif

          Distribution information

          Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
          Terms and conditions for distribution The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.(Hum. Gene Ther., 13, 613-626 (2002); Cancer Gene Ther., 10, 75-85 (2003).) In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
          Additional terms and conditions:
          Regarding resources containing CAG promoter: In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation for the CAG promoter (Niwa, H., Yamamura, K., Miyazaki, J., Gene 108 : 193-200, 1991) and an acknowledgment to Dr. Jun-ich Miyazaki of the Osaka University are requested.
          提供案内 (日本国内) [open/close]

          提供条件 非営利機関の非営利学術研究へ提供する。利用者が本件リソースを利用した研究成果に基づき特許申請、商業活動等を行う場合は、利用者は事前に寄託者に連絡する。利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する(Hum. Gene Ther., 13, 613-626 (2002); Cancer Gene Ther., 10, 75-85 (2003).)。利用者は、研究成果の公表にあたって謝辞の表明を必要とする。
          付加的提供条件：
          CAGプロモータを含むリソースについて: 利用者は、研究成果の公表にあたってCAGプロモータの文献 (Niwa, H., Yamamura, K., Miyazaki, J., Gene 108 : 193-200, 1991)を引用し、大阪大学 宮崎純一博士への謝辞の表明を必要とする。
          備考 【追加提供依頼書】受入れ確認書(書式J)
          組換え体提供にかかる書式が必要です。

          Catalog # Resource name Availability Shipping form Fee (non-profit org.)
          RDB02194 AxCAZ3-F/RGD Under QC test. Please contact us. Virus, lysate of infected cell culture Please contact us.

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          How to cite this biological resource

          Materials & Methods section:

          The AxCAZ3-F/RGD was provided by the RIKEN BRC through the National BioResource Project of the MEXT, Japan (cat. RDB02194).

          Reference section:

          Dehari, H., Ito, Y., Nakamura, T., Kobune, M., Sasaki, K., Yonekura, N., Kohama, G., Hamada, H., Enhanced antitumor effect of RGD fiber-modified adenovirus for gene therapy of oral cancer. Cancer Gene Ther., 10, 75-85 (2003). PMID 12489031.
          Nakamura, T., Sato, K., Hamada, H., Effective gene transfer to human melanomas via integrin-targeted adenoviral vectors. Hum. Gene Ther., 13, 613-626 (2002). PMID 11916485.

          Further references such as user reports and related articles (go to bottom)

          References and tips

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          Featured content Arranged vector (English text)

          QC test results

          References

          Original, user report and related articles

          original Dehari, H., Enhanced antitumor effect of RGD fiber-modified adenovirus for gene therapy of oral cancer. Cancer Gene Ther., 10, 75-85 (2003). PMID 12489031.
          original Nakamura, T., Effective gene transfer to human melanomas via integrin-targeted adenoviral vectors. Hum. Gene Ther., 13, 613-626 (2002). PMID 11916485.
          user_report Shen, Y.H., Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice. PLoS One. 11 (1): e0147173 (2016). PMID 26799485.
          user_report Wakayama M., E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers. Clin. Cancer Res., 13, 3043-3050 (2007). PMID 17505007.

          2023.05.02

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