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Ax1w1

A control virus with deletions of ElA, ElB and E3 genes

Catalog number RDB01746
Resource name Ax1w1
Clone info. A control virus with deletions of E1A, E1B and E3 genes and bearing no insert
Vector backbone pAxcw (Adenovirus)
Size of vector backbone -
Growth remarks 5 percent FCS is fine.
Gene/insert name AdV_5 -
Depositor|Developer Saito, Izumu |

Distribution information

Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
Terms and conditions set forth by the DEPOSITOR In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature designated by the DEPOSITOR is requested (Miyake, S., Proc. Natl. Acad. Sci. USA, 93, 1320-1324(1996)).
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Material Transfer Agreement (MTA for use for not-for-profit academic purpose) [Word]
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Catalog # Resource name Availability Shipping form Fee (non-profit org.)
RDB01746 Ax1w1 Under QC test. Please contact us. Please contact us.

check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.
Ordering Information [in Japanese] [in English]

References and tips

Electronic file

Electronic file Map RDB01746.gif

Original reference

original Miyake, S., Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA, 93, 1320-1324 (1996). PMID 8577762.

Further references such as user reports and related articles (go to bottom)

Featured content

Sequence information

References

Original, user report and related articles

original Miyake, S., Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA, 93, 1320-1324 (1996). PMID 8577762.
reference Niwa, H., Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108 (2): 193-199 (1991). PMID 1660837.
user report Fukuda K., E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer. Cancer Gene Ther., 16, 126-136 (2009). PMID 18818710.
user report Wakayama M., E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers. Clin. Cancer Res., 13, 3043-3050 (2007). PMID 17505007.
user report Hayakawa Y., Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells. J. Thromb. Haemost., 5, 2219-2226 (2007). PMID 17958740.
user report Nonomura Y., Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6. Arthritis Rheum., 54, 2074-2083 (2006). PMID 16802342.
user report Hayakawa Y., Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular responses in fibroblasts and vascular smooth muscle cells. Thromb. Res., 116, 357-363 (2005). PMID 16038721.
user report Fukuda K., E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. Cancer Res., 63, 4434-4440 (2003). PMID 12907616.
user report Nonomura Y., Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis. J. Immunol., 171, 4913-4919 (2003). PMID 14568973.
user report Nonomura Y., Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints. Int. Immunol., 13, 723-731 (2001). PMID 11369699.
user report Hirashima Y., Transfection of the plasma-type platelet-activating factor acetylhydrolase gene attenuates glutamate-induced apoptosis in cultured rat cortical neurons. Brain Res., 885, 128-132 (2000). PMID 11121539.

2021.03.25

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