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Ax1w1

A control virus with deletions of ElA, ElB and E3 genes

Catalog number RDB01746
Resource name Ax1w1
Clone info. A control virus with deletions of E1A, E1B and E3 genes and bearing no insert
Vector backbone pAxcw (Adenovirus)
Size of vector backbone -
Growth remarks 5 percent FCS is fine.
Gene/insert name AdV_5 -
Depositor|Developer Saito, Izumu |
Other clones in our bank
External Database
AdV_5 -
            Reference sequence
              
             
            Remarks, protocol and/or map (gif) RDB01746.gif

            Distribution information

            Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
            Terms and conditions for distribution In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature designated by the DEPOSITOR is requested (Miyake, S., Proc. Natl. Acad. Sci. USA, 93, 1320-1324(1996)).
            Ordering Please visit Information of Request for Distribution.[link] For for-profit-research purpose, please contact us. 
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            Material Transfer Agreement (MTA for use for not-for-profit academic purpose) [Word]
            提供案内 (日本国内) [open/close]

            提供条件 利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する (Miyake, S., Proc. Natl. Acad. Sci. USA, 93, 1320-1324(1996))。
            提供依頼 手続きの詳細は、「提供申込みについて[link]」をご覧ください。営利目的利用についてはお問い合わせください。
            提供依頼書 [Word]
            提供同意書 (MTA、非営利機関による非営利学術研究用)[Word]
            遺伝子組換え生物の受入れ確認書 [Word]
            備考 【追加提供依頼書】受入れ確認書(書式J)
            組換え体提供にかかる書式が必要です。

            Catalog # Resource name Availability Shipping form Fee (non-profit org.)
            RDB01746 Ax1w1 Under QC test. Please contact us. Virus, lysate of infected cell culture

            check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

            How to cite this biological resource

            Materials & Methods section:

            The Ax1w1 was provided by the RIKEN BRC through the National BioResource Project of the MEXT, Japan (cat. RDB01746).

            Reference section:

            Miyake, S., Makimura, M., Kanegae, Y., Harada, S., Sato, Y., Takamori, K., Tokuda, C., Saito, I., Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA, 93, 1320-1324 (1996). PMID 8577762.

            Further references such as user reports and related articles (go to bottom)

            References and tips

            Featured content

            QC test results

            References

            Original, user report and related articles

            original Miyake, S., Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc. Natl. Acad. Sci. USA, 93, 1320-1324 (1996). PMID 8577762.
            reference Niwa, H., Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene, 108 (2): 193-200 (1991). PMID 1660837.
            user_report Fukuda K., E1A, E1B double-restricted replicative adenovirus at low dose greatly augments tumor-specific suicide gene therapy for gallbladder cancer. Cancer Gene Ther., 16, 126-136 (2009). PMID 18818710.
            user_report Wakayama M., E1A, E1B double-restricted adenovirus with RGD-fiber modification exhibits enhanced oncolysis for CAR-deficient biliary cancers. Clin. Cancer Res., 13, 3043-3050 (2007). PMID 17505007.
            user_report Hayakawa Y., Thrombin-induced cell proliferation and platelet-derived growth factor-AB release from A172 human glioblastoma cells. J. Thromb. Haemost., 5, 2219-2226 (2007). PMID 17958740.
            user_report Nonomura Y., Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6. Arthritis Rheum., 54, 2074-2083 (2006). PMID 16802342.
            user_report Hayakawa Y., Adenovirus-mediated expression of heparin cofactor II inhibits thrombin-induced cellular responses in fibroblasts and vascular smooth muscle cells. Thromb. Res., 116, 357-363 (2005). PMID 16038721.
            user_report Fukuda K., E1A, E1B double-restricted adenovirus for oncolytic gene therapy of gallbladder cancer. Cancer Res., 63, 4434-4440 (2003). PMID 12907616.
            user_report Nonomura Y., Gene transfer of a cell cycle modulator exerts anti-inflammatory effects in the treatment of arthritis. J. Immunol., 171, 4913-4919 (2003). PMID 14568973.
            user_report Nonomura Y., Suppression of arthritis by forced expression of cyclin-dependent kinase inhibitor p21(Cip1) gene into the joints. Int. Immunol., 13, 723-731 (2001). PMID 11369699.
            user_report Hirashima Y., Transfection of the plasma-type platelet-activating factor acetylhydrolase gene attenuates glutamate-induced apoptosis in cultured rat cortical neurons. Brain Res., 885, 128-132 (2000). PMID 11121539.

            2023.05.02

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