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pGEMhIL-6 GT

Human IL-6 genomic clone

Catalog number RDB01211
Resource name pGEMhIL-6 GT
Alternative name Human IL-6 genomic clone
Clone info. Human IL-6 genomic clone from human tonsillar mononuclear cells library
Vector backbone pGEM-4 (Plasmid)
Size of vector backbone 2,871 bp
Selectable markers Amp^r
Gene/insert name Human IL6 Genomic DNA
Depositor|Developer Akira, Shizuo |
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External Database
Human IL6

          Reference sequence
            

          Distribution information

          Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
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          RDB01211 pGEMhIL-6 GT Under QC test. Please contact us. DNA solution Please contact us.

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.
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          References and tips

          Electronic file

          Remarks, protocol and/or map (gif) RDB01211.gif

          Original reference

          original Yasukawa, K., Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J., 6, 2939-2945 (1987). PMID 3500852.

          Further references such as user reports and related articles (go to bottom)

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          Sequence information

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.


          References

          Original, user report and related articles

          original Yasukawa, K., Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J., 6, 2939-2945 (1987). PMID 3500852.
          user report Miyazawa K., IL-6 synthesis by rheumatoid synoviocytes is autonomously upregulated at the transcriptional level. J. Allergy Clin. Immunol., 103, S437-444 (1999). PMID 10329846.
          user report Miyazawa K., Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. Am. J. Pathol., 152, 793-803 (1998). PMID 9502421.
          user report Miyazawa K., Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. J. Biol. Chem., 273, 7620-7627 (1998). PMID 9516466.
          user report Miyazawa K., Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J. Biol. Chem., 273, 24832-24838 (1998). PMID 9733787.

          2022.02.09

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