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pGEMhIL-6 GT

Human IL-6 genomic clone

Catalog number RDB01211
Resource name pGEMhIL-6 GT
Alternative name Human IL-6 genomic clone
Clone info. Human IL-6 genomic clone from human tonsillar mononuclear cells library
Vector backbone pGEM-4 (Plasmid)
Size of vector backbone 2,871 bp
Selectable markers Amp^r
Gene/insert name Human IL6 Genomic DNA
Depositor|Developer Akira, Shizuo |
Other clones in our bank
External Database
Human IL6
          Reference sequence
            
           
          Remarks, protocol and/or map (gif) RDB01211.gif

          Distribution information

          Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
          Terms and conditions for distribution In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature(s) designated by the DEPOSITOR is requested.
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          提供条件 利用者は、研究成果の公表にあたって寄託者の指定する文献を引用する。
          提供依頼 手続きの詳細は、「提供申込みについて[link]」をご覧ください。営利目的利用についてはお問い合わせください。
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          RDB01211 pGEMhIL-6 GT Under QC test. Please contact us. DNA solution Please contact us.

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          How to cite this biological resource

          Materials & Methods section:

          The pGEMhIL-6 GT was provided by the RIKEN BRC through the National BioResource Project of the MEXT, Japan (cat. RDB01211).

          Reference section:

          Yasukawa, K., Hirano, T., Watanabe, Y., Muratani, K., Matsuda, T., Nakai, S., Kishimoto, T., Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J., 6, 2939-2945 (1987). PMID 3500852.

          Further references such as user reports and related articles (go to bottom)

          References and tips

          Featured content

          QC test results

          check Please wait for results of QC test to be uploaded. This clone will be sequenced a portion for examination.

          References

          Original, user report and related articles

          original Yasukawa, K., Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J., 6, 2939-2945 (1987). PMID 3500852.
          user_report Miyazawa K., IL-6 synthesis by rheumatoid synoviocytes is autonomously upregulated at the transcriptional level. J. Allergy Clin. Immunol., 103, S437-444 (1999). PMID 10329846.
          user_report Miyazawa K., Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. Am. J. Pathol., 152, 793-803 (1998). PMID 9502421.
          user_report Miyazawa K., Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. J. Biol. Chem., 273, 7620-7627 (1998). PMID 9516466.
          user_report Miyazawa K., Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J. Biol. Chem., 273, 24832-24838 (1998). PMID 9733787.

          2023.05.02

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