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pGEMhIL-6 GT

Human IL-6 genomic clone

Catalog number RDB01211
Resource name pGEMhIL-6 GT
Alternative name Human IL-6 genomic clone
Clone info. Human IL-6 genomic clone from human tonsillar mononuclear cells library
Vector backbone pGEM-4 (Plasmid)
Size of vector backbone 2,871 bp
Selectable markers Amp^r
Gene/insert name Human IL6 Genomic DNA
Depositor Akira, Shizuo |
 
Other clones in our bank human IL6 (NCBI Gene 3569) |

Distribution information

Please check terms and conditions set forth by the depositor, which are specified in the RIKEN BRC Catalog and/or Web Catalog.
Terms and conditions set forth by the DEPOSITOR In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of literature(s) designated by the DEPOSITOR is requested.
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Catalog # Resource name Availability Shipping form Fee (non-profit org.)
RDB01211 pGEMhIL-6 GT Under QC test. Please contact us. DNA solution Please contact us.

Ordering Information [in Japanese] [in English]

References and tips

Electronic file

Electronic file Map RDB01211.gif from Depositor

Original reference

original Yasukawa, K., Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J., 6, 2939-2945 (1987). PMID 3500852.

Further references such as user reports and related articles (go to bottom)

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Sequence information

This clone will be sequenced a portion and digested by restriction enzyme for examination.

References

Original, user report and related articles

original Yasukawa, K., Structure and expression of human B cell stimulatory factor-2 (BSF-2/IL-6) gene. EMBO J., 6, 2939-2945 (1987). PMID 3500852.
user report Miyazawa K., IL-6 synthesis by rheumatoid synoviocytes is autonomously upregulated at the transcriptional level. J. Allergy Clin. Immunol., 103, S437-444 (1999). PMID 10329846.
user report Miyazawa K., Constitutive transcription of the human interleukin-6 gene by rheumatoid synoviocytes: spontaneous activation of NF-kappaB and CBF1. Am. J. Pathol., 152, 793-803 (1998). PMID 9502421.
user report Miyazawa K., Transcriptional roles of CCAAT/enhancer binding protein-beta, nuclear factor-kappaB, and C-promoter binding factor 1 in interleukin (IL)-1beta-induced IL-6 synthesis by human rheumatoid fibroblast-like synoviocytes. J. Biol. Chem., 273, 7620-7627 (1998). PMID 9516466.
user report Miyazawa K., Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J. Biol. Chem., 273, 24832-24838 (1998). PMID 9733787.

2019.10.05

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